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48186-01 - Lecture: Laser and Optics in Medicine 6 CP

Semester spring semester 2020
Course frequency Every spring sem.
Lecturers Ferda Canbaz (ferda.canbaz@unibas.ch)
Azhar Zam (azhar.zam@unibas.ch, Assessor)
Content Introduction:
Nature of light, fundamentals of light-matter interactions, photobiology, photophysics, photochemistry, laser and light sources, laser safety.

Light-Tissue Interactions:
Photochemical interaction, biostimulation, photo-thermal effects, photoablation, plasma-induced ablation, photo-acoustic effects, photon transport, monte carlo simulations, adding doubling method.

Spectroscopy:
Absorption, diffuse reflectance, fluorescence, Raman and tissue spectroscopy

Biosensors:
Principles of optical biosensing, optical geometries for biosensors and biosensing methods.

Bioimaging Principles and Techniques:
Introduction to optical microscopy, principle of image formation, amplitude and phase microscopy, polarization, fluorescence and confocal microscopy, optical diffraction tomography and new microscopic techniques.

2D Bioimaging:
Endoscopy, videomicroscopy, diffuse reflectance, laser Doppler perfusion imaging, laser speckle perfusion imaging, .

3D Bioimaging:
Optical coherence tomography, polarimetry, diffuse optical tomography, photothermal imaging, photoacoustic imaging and optical biopsy.

Applications Laser and Optics in Medicine and Biology:
Biophotonics applications in medicine, laser tweezers and scissors, microarray and microfluidic technologies for genomics and proteomics, flow cytometry, bioluminescence, bio-nanophotonics, opto-genetics, tissue engineering with light and data analysis in Biophotonics.
Bibliography Recommended Reading:
Prasad, P.N., “Introduction to Biophotonics”, (Wiley-VCH), 2003
Wang, LV and Wu HI, Biomedical Optics, Principles and Imaging, (Wiley-VCH), 2007,
Demchenko, A P "Introduction to Fluorescence Sensing", Springer, 2008
Popp,Tuchin, Chiou, Heinemann (Editors) Handbook of Biophotonics, 3 Volume Set, (Wiley-VCH), 2012.
Leahy, M.J. editor, Microcirculation Imaging, (Wiley-VCH), 2012.
Weblink DBE

 

Language of instruction English
Use of digital media No specific media used

 

Interval weekly
Date 19.02.2020 – 27.05.2020
Time Wednesday, 09.00-11.45 Gewerbestrasse 14, Vorlesungsraum DBE 14.03.002
Date Time Room
Wednesday 19.02.2020 09.00-11.45 Gewerbestrasse 14, Vorlesungsraum DBE 14.03.002
Wednesday 26.02.2020 09.00-11.45 Gewerbestrasse 14, Vorlesungsraum DBE 14.03.002
Wednesday 04.03.2020 09.00-11.45 Fasnachtsferien
Wednesday 11.03.2020 09.00-11.45 Gewerbestrasse 14, Vorlesungsraum DBE 14.03.002
Wednesday 18.03.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 25.03.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 01.04.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 08.04.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 15.04.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 22.04.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 29.04.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 06.05.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 13.05.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 20.05.2020 09.00-11.45 Gewerbestrasse 14, --
Wednesday 27.05.2020 09.00-11.45 Gewerbestrasse 14, --
Modules Doctorate Biomedical Engineering: Recommendations (PhD subject Biomedical Engineering)
Module: Biomaterials Science and Nanotechnology (Master's Studies: Biomedical Engineering)
Module: Image-Guided Therapy (Master's Studies: Biomedical Engineering)
Assessment format proof of course participation
Assessment details Attendance 25%, Practical Work 20%, Quiz 15% and Final oral Exam 40%.
Assessment registration/deregistration Reg./dereg.: course registr./cancel registr. via MOnA
Repeat examination one repetition, best attempt counts
Scale 1-6 0,5
Repeated registration as often as necessary
Responsible faculty Faculty of Medicine
Offered by Departement Biomedical Engineering (DBE)

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