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Semester | fall semester 2021 |
Course frequency | Every fall sem. |
Lecturers |
Philip Bentley (philip.bentley@unibas.ch)
Alex Odermatt (alex.odermatt@unibas.ch, Assessor) |
Content | The major themes of the course are bioanalytical method development and validation, drug disposition and biotransformation, and the use of radioisotopes in generating this information, pharmacokinetics, pharmacokinetic modelling and drug-drug interactions. |
Learning objectives | The course demonstrates the characterization of drug disposition within the drug discovery and development process and illustrates how the information is used for drug candidate selection and eventually product registration. It provides an understanding of how data generated in in vitro and animals studies is used to predict the disposition of a drug candidate in humans, including the therapeutic dose and potential drug-drug interactions, and demonstrates how pharmacokinetic models are refined once human data is available. |
Bibliography | Deutsch: • Allgemeine und spezielle Pharmakologie und Toxikologie herausgegeben von Forth/Henschler/Rummel usw. Urban & Fischer , München - Jena • Pharmakokinetik kompakt Derendorf-Gramatté-Schäfer-Staab Wissenschaftliche Verlagsgesellschaft Stuttgart English: • Preclinical Drug Disposition, a laboratory handbook Francis L.S Tse & James M. Jaffe Drugs and the Pharmaceuticals Sciences, Vol. 46. Marcel Dekker, Inc • Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for industrial Scientists Younggil Kwon Kluwer Academic /Plenum Publishers • Clinical Pharmacokinetics: Concepts and Applications Malcolm Rowland & Thomas N. Tozer Lippincott Williams & Wilkins |
Comments | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated) |
Weblink | https://adam.unibas.ch/goto_adam_crs_111 |
Admission requirements | Completed Bachelor degree |
Language of instruction | English |
Use of digital media | No specific media used |
Interval | Weekday | Time | Room |
---|---|---|---|
wöchentlich | Friday | 10.15-12.00 | - Online Präsenz - |
Date | Time | Room |
---|---|---|
Friday 12.11.2021 | 10.15-12.00 | - Online Präsenz -, -- |
Friday 19.11.2021 | 10.15-12.00 | - Online Präsenz -, -- |
Friday 26.11.2021 | 10.15-12.00 | Dies Academicus |
Friday 03.12.2021 | 10.15-12.00 | - Online Präsenz -, -- |
Friday 10.12.2021 | 10.15-12.00 | - Online Präsenz -, -- |
Friday 17.12.2021 | 10.15-12.00 | - Online Präsenz -, -- |
Friday 24.12.2021 | 10.15-12.00 | Weihnachtsferien |
Modules |
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy) Module: Translating Pharmacology and Drug Safety to Humans (Master's Studies: Drug Sciences) |
Assessment format | continuous assessment |
Assessment details | https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
Repeat examination | no repeat examination |
Scale | 1-6 0,5 |
Repeated registration | as often as necessary |
Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
Offered by | Departement Pharmazeutische Wissenschaften |