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| Semester | Frühjahrsemester 2019 |
| Angebotsmuster | Jedes Frühjahrsem. |
| Dozierende | Mihaela Zavolan (mihaela.zavolan@unibas.ch, BeurteilerIn) |
| Inhalt | The course introduces fundamental concepts and algorithms in bioinformatics. More specifically, it covers the following topics: • Evolution: definitions, mathematical models describing evolution of large and small populations. • Phylogeny: reconstructing the evolutionary relationships between species based on their genomic sequences. • Sequence alignments: the pairwise and multiple sequence alignment problems. • Functional annotation: Finding genes and regulatory sequences in the genome. • Describing relationships between protein sequences: Hidden Markov models of protein domains • Functional RNAs: RNA secondary structure and annotation of functional RNAs • Gene expression analysis: Inferring the relative abundance of RNA molecules from RNA sequencing data |
| Lernziele | Students learn about the basic problem domain of bioinformatics as well as a wide range of algorithms for sequence analysis. They will learn about the commonly used languages of bioinformatics (mostly Python) and will implement basic bioinformatics algorithms. |
| Weblink | https://adam.unibas.ch |
| Teilnahmebedingungen | First year courses must be accomplished. Mathematical background is needed in calculus, linear algrebra, diffential equations. Knowledge about discrete mathematics, stochastic processes and fundamental computer science algorithms is a plus. Basic programming skills and basic understanding in physics, chemistry and molecular biology (cells, DNA, RNA, proteins, etc.) is necessary. |
| Unterrichtssprache | Englisch |
| Einsatz digitaler Medien | kein spezifischer Einsatz |
| Intervall | Wochentag | Zeit | Raum |
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Keine Einzeltermine verfügbar, bitte informieren Sie sich direkt bei den Dozierenden.
| Module |
Cycle E: Computational and Systems Biology (Masterstudium: Molekularbiologie) Modul: Applications and Related Topics (Bachelorstudium: Computer Science) Modul: Computational Biology (Bachelorstudium: Computational Sciences) (Pflicht) Modul: Computational Chemistry (Bachelorstudium: Computational Sciences) Modul: Computational Physics (Bachelorstudium: Computational Sciences) Modul: Computational Sciences II (Bachelorstudium: Computational Sciences) Vertiefungsmodul: Bioinformatik (Bachelorstudium: Informatik (Studienbeginn vor 01.08.2010)) (Pflicht) Vertiefungsmodul: Computational Intelligence (Bachelorstudium: Informatik (Studienbeginn vor 01.08.2016)) Vertiefungsmodul: Computer Science (Bachelorstudium: Informatik (Studienbeginn vor 01.08.2010)) Vertiefungsmodul: Life Science-Informatik (Bachelorstudium: Informatik (Studienbeginn vor 01.08.2016)) |
| Leistungsüberprüfung | Lehrveranst.-begleitend |
| Hinweise zur Leistungsüberprüfung | Written exam and exercises Exam: Monday, 27.5.2019, 13:00–14:00h; Lounge, Klingelbergstrasse 61, room 1301, floor E13 |
| An-/Abmeldung zur Leistungsüberprüfung | Anm.: Belegen Lehrveranstaltung; Abm.: stornieren |
| Wiederholungsprüfung | keine Wiederholungsprüfung |
| Skala | 1-6 0,5 |
| Wiederholtes Belegen | beliebig wiederholbar |
| Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
| Anbietende Organisationseinheit | Departement Biozentrum |