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Semester | Frühjahrsemester 2020 |
Angebotsmuster | Jedes Frühjahrsem. |
Dozierende | Christian M.H.R. de Geyter (c.degeyter@unibas.ch, BeurteilerIn) |
Inhalt | Week 1: Embryogenesis and sexual differentation I & II Week 2: Gonadal function: testes, ovaries, hormonal circuits; Toxic effects on gonads: protective measures (blood testis barrier, biotransformation, DNArepair) examples of toxicity Week 3: Testing male reproductive function: animals and humans; Testing female reproductive function: animals and humans Week 4: Placenta: transport of drugs, biotransformation, models; Prenatal toxicity and teratogenicity: mechanisms and examples I Week 5: Prenatal toxicity and teratogenicity: mechanisms and examples II; Peri- and postnatal toxicities, lactation Week 6: Regulatory requirements; In vitro systems and animal models Week 7: Exam |
Lernziele | to understand the basic endocrine pathways in the regulation of reproduction in the female and in the male to understand the endocrine pathways in pregnancy to be able to outline embryogenesis and sexual differentiation to understand potential toxic effects of a number of compounds in reproductive toxicology and its mechanisms of action in the gonads, in the embryo & the placenta and during lactation to be able to describe the evaluation systems in use in reproductive toxicology |
Literatur | Toxicology, The Basic Science of Poisons, Eds. Casarett & Doull's |
Bemerkungen | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated |
Weblink | www.ivf-basel.ch |
Teilnahmebedingungen | Completed Bachelor degree |
Unterrichtssprache | Englisch |
Einsatz digitaler Medien | kein spezifischer Einsatz |
Intervall | Wochentag | Zeit | Raum |
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Keine Einzeltermine verfügbar, bitte informieren Sie sich direkt bei den Dozierenden.
Module |
Modul: Translating Pharmacology and Drug Safety to Humans (Masterstudium: Drug Sciences) Wahlbereich Master Pharmazie: Empfehlungen (Masterstudium: Pharmazie) |
Leistungsüberprüfung | Lehrveranst.-begleitend |
Hinweise zur Leistungsüberprüfung | Please refer to the list: https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
An-/Abmeldung zur Leistungsüberprüfung | Anm.: Belegen Lehrveranstaltung; Abm.: stornieren |
Wiederholungsprüfung | keine Wiederholungsprüfung |
Skala | 1-6 0,5 |
Wiederholtes Belegen | beliebig wiederholbar |
Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
Anbietende Organisationseinheit | Departement Pharmazeutische Wissenschaften |