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50310-01 - Vorlesung mit Übungen: Analytical Applications in Drug Discovery 1 KP

Semester Frühjahrsemester 2020
Angebotsmuster Jedes Frühjahrsem.
Dozierende Stephan Müller (stephan.mueller@unibas.ch, BeurteilerIn)
Inhalt Examples for typical topics:
Introduction and toolbox: What to find where. Suppliers, literature, information, software
Advanced HPLC methods: UPLC, column materials, column switching
Application quantitative Bioanalysis; HPLC-UV
Method validation example
Advanced mass spectrometry: accurate mass and elemental composition; application in qualitative analysis
Advanced MS/MS experiments, data dependent analysis, ion mobility; application in chemical, biochemical and -omics analysis
noncovalent interaction analysis; application in binding assays
Application Biomarker Analysis; LC/MS-MS*
Application compound purity assessment workflow*

*if permission is granted and time sufficient
Lernziele Insight and beginner's experience of analytical practise in research: You know material and information sources and providers, you can search, manage and extract literature on practical examples and derive a proposal for method development. You can use Excel for the evaluation of typical amounts of data and have to do some troubleshooting. You learn some more on advanced instrumental analytics, especially mass spectrometry.
Literatur Literature: Will mostly have to be looked up..
Bemerkungen THE course for you digital natives :-)

Film and sound recordings during the course are strictly forbidden (recorders may be confiscated)
Weblink Participants webpage, please register


Teilnahmebedingungen Completed Bachelor degree
Beside the usual booking over MonA registration under unibas.smv3.ch is needed!

Laptop with power supply for 2h during the lessons
Recent MS Office software or equivalent
Standard web browser (Safari, Firefox, Chrome, MSE)
Structure Editor: Download and install ChemAxon's Marvin suite for structure design.
Scientific calculator
Anmeldung zur Lehrveranstaltung 1. University booking (Belegen) as usual over MoNa
2. Register at unibas.smv3.ch to access the software and material download
Unterrichtssprache Englisch
Einsatz digitaler Medien Online-Veranstaltung
HörerInnen willkommen


Intervall wöchentlich
Datum 25.02.2020 – 07.04.2020
Zeit Dienstag, 15.15-17.00 Biozentrum, Seminarraum 104
Datum Zeit Raum
Dienstag 25.02.2020 15.15-17.00 Uhr Biozentrum, Seminarraum 104
Dienstag 03.03.2020 15.15-17.00 Uhr Fasnachtsferien
Dienstag 10.03.2020 15.15-17.00 Uhr Biozentrum, Seminarraum 104
Dienstag 17.03.2020 15.15-17.00 Uhr Biozentrum, Findet online statt
Dienstag 24.03.2020 15.15-17.00 Uhr Biozentrum, Findet online statt
Dienstag 31.03.2020 15.15-17.00 Uhr Biozentrum, Findet online statt
Dienstag 07.04.2020 15.15-17.00 Uhr Biozentrum, Findet online statt
Module Wahlbereich Master Drug Sciences: Empfehlungen (Masterstudium: Drug Sciences)
Wahlbereich Master Pharmazie: Empfehlungen (Masterstudium: Pharmazie)
Leistungsüberprüfung Lehrveranst.-begleitend
Hinweise zur Leistungsüberprüfung The examination will take place in form of exercises or online or paper quizzes during the lessons. The tasks will require informatics tools and internet access. Therefore, registration at unibas.smv3.ch and a PC/Mac with web access and MS Office during the lessons is mandatory.
An-/Abmeldung zur Leistungsüberprüfung An-/Abmelden: Belegen resp. Stornieren der Belegung via MOnA
Wiederholungsprüfung keine Wiederholungsprüfung
Skala Pass / Fail
Wiederholtes Belegen beliebig wiederholbar
Zuständige Fakultät Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch
Anbietende Organisationseinheit Departement Pharmazeutische Wissenschaften