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50310-01 - Vorlesung mit Übungen: Analytical Applications in Drug Discovery (1 KP)

Semester Frühjahrsemester 2020
Angebotsmuster Jedes Frühjahrsem.
Dozierende Stephan Müller (stephan.mueller@unibas.ch, BeurteilerIn)
Inhalt Examples for typical topics:
Introduction and toolbox: What to find where. Suppliers, literature, information, software
Advanced HPLC methods: UPLC, column materials, column switching
Application quantitative Bioanalysis; HPLC-UV
Method validation example
Advanced mass spectrometry: accurate mass and elemental composition; application in qualitative analysis
Advanced MS/MS experiments, data dependent analysis, ion mobility; application in chemical, biochemical and -omics analysis
noncovalent interaction analysis; application in binding assays
Application Biomarker Analysis; LC/MS-MS*
Application compound purity assessment workflow*

*if permission is granted and time sufficient
Lernziele Insight and beginner's experience of analytical practise in research: You know material and information sources and providers, you can search, manage and extract literature on practical examples and derive a proposal for method development. You can use Excel for the evaluation of typical amounts of data and have to do some troubleshooting. You learn some more on advanced instrumental analytics, especially mass spectrometry.
Literatur Literature: Will mostly have to be looked up..
Bemerkungen THE course for you digital natives :-)

Film and sound recordings during the course are strictly forbidden (recorders may be confiscated)
Weblink Participants webpage, please register

 

Teilnahmevoraussetzungen Completed Bachelor degree
Beside the usual booking over MonA registration under unibas.smv3.ch is needed!

Laptop with power supply for 2h during the lessons
Recent MS Office software or equivalent
Standard web browser (Safari, Firefox, Chrome, MSE)
Structure Editor: Download and install ChemAxon's Marvin suite for structure design.
Scientific calculator
Anmeldung zur Lehrveranstaltung 1. University booking (Belegen) as usual over MoNa
2. Register at unibas.smv3.ch to access the software and material download
Unterrichtssprache Englisch
Einsatz digitaler Medien Online-Veranstaltung
HörerInnen willkommen

 

Intervall Wochentag Zeit Raum

Keine Einzeltermine verfügbar, bitte informieren Sie sich direkt bei den Dozierenden.

Module Wahlbereich Master Drug Sciences: Empfehlungen (Masterstudium: Drug Sciences)
Wahlbereich Master Pharmazie: Empfehlungen (Masterstudium: Pharmazie)
Prüfung Lehrveranst.-begleitend
Hinweise zur Prüfung The examination will take place in form of exercises or online or paper quizzes during the lessons. The tasks will require informatics tools and internet access. Therefore, registration at unibas.smv3.ch and a PC/Mac with web access and MS Office during the lessons is mandatory.
An-/Abmeldung zur Prüfung Anm.: Belegen Lehrveranstaltung; Abm.: stornieren
Wiederholungsprüfung keine Wiederholungsprüfung
Skala Pass / Fail
Belegen bei Nichtbestehen beliebig wiederholbar
Zuständige Fakultät Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch
Anbietende Organisationseinheit Departement Pharmazeutische Wissenschaften

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