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14429-01 - Vorlesung: Development of Therapeutic Antibodies 1 KP

Semester Herbstsemester 2022
Angebotsmuster Jedes Herbstsemester
Dozierende Steffen Hartmann (steffen.hartmann@unibas.ch)
Thomas Huber (thomas.huber@unibas.ch)
Frank Kolbinger (frank.kolbinger@unibas.ch)
Roland Preston (roland.preston@unibas.ch)
Daniel Ricklin (d.ricklin@unibas.ch, BeurteilerIn)
Maximilian Woisetschläger (maximilian.woisetschlaeger@unibas.ch)
Inhalt Therapeutic antibodies have evolved into a highly important and rapidly growing sector of modern drug therapy, with several antibody-based drugs being available to the clinic and many more in clinical development. In this lecture series, experts from pharmaceutical industry with broad experience in antibody development will guide through the various aspects of bringing a therapeutic antibody from discovery to the clinic. In particular, the lectures will cover the following topics:
- Structure and characteristics of immunoglobulins, and generation of monoclonal antibodies
- Effector functions and pharmacokinetic properties of antibodies
- Preclinical development, characterization and production of therapeutic antibodies
- Clinical development and therapeutic use of antibody-based therapeutics
- Examples and case studies of therapeutic antibodies in the clinic
- Emerging trends in the discovery and development of antibody-based drugs

Depending on the pandemic situation, a guided tour at one of Novartis’ antibody facilities may be organized. A special announcement will be made to provide more information.
Lernziele During this lecture series, the students will learn about:
- the key structural, functional and pharmaceutical features of antibodies
- established and emerging strategies to design antibody-based drugs
- options to produce antibodies at the laboratory or industrial scale
- considerations and examples of using therapeutic antibodies in the clinic
Bemerkungen Film and sound recordings during the course are strictly forbidden (recording devices may be confiscated)
Weblink Department of Pharmaceutical Care


Teilnahmebedingungen Completed Bachelor degree
Unterrichtssprache Englisch
Einsatz digitaler Medien kein spezifischer Einsatz


Intervall wöchentlich
Datum 09.11.2022 – 21.12.2022
Zeit Mittwoch, 10.15-12.00 Biozentrum, Seminarraum U1.191
Datum Zeit Raum
Mittwoch 09.11.2022 10.15-12.00 Uhr Biozentrum, Seminarraum U1.191
Mittwoch 16.11.2022 10.15-12.00 Uhr Biozentrum, Seminarraum U1.191
Mittwoch 23.11.2022 10.15-12.00 Uhr Biozentrum, Seminarraum U1.191
Mittwoch 30.11.2022 10.15-12.00 Uhr Biozentrum, Seminarraum U1.191
Mittwoch 07.12.2022 10.15-12.00 Uhr Biozentrum, Seminarraum U1.191
Mittwoch 14.12.2022 10.15-12.00 Uhr Biozentrum, Seminarraum U1.191
Mittwoch 21.12.2022 09.00-10.00 Uhr Biozentrum, Hörsaal U1.131, Prüfung
Module Modul: Target Identification/Validation to Discovery of Modulators (Masterstudium: Drug Sciences)
Modul: Vertiefung Medizinische Nanowissenschaften (Masterstudium: Nanowissenschaften)
Wahlbereich Master Pharmazie: Empfehlungen (Masterstudium: Pharmazie)
Leistungsüberprüfung Lehrveranst.-begleitend
Hinweise zur Leistungsüberprüfung Electronic written examination at the end of the semester (60 min, iPad)
An-/Abmeldung zur Leistungsüberprüfung Anm.: Belegen Lehrveranstaltung; Abm.: stornieren
Wiederholungsprüfung keine Wiederholungsprüfung
Skala 1-6 0,5
Wiederholtes Belegen beliebig wiederholbar
Zuständige Fakultät Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch
Anbietende Organisationseinheit Departement Pharmazeutische Wissenschaften