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18367-01 - Vorlesung: Translational Control and Post-Translational Protein Modification (2 KP)
| Semester | Herbstsemester 2013 |
| Angebotsmuster | unregelmässig |
| Dozierende |
Michael N. Hall (m.hall@unibas.ch, BeurteilerIn)
Jan Hofsteenge (jan.hofsteenge@fmi.ch) Paul Jenö (paul.jenoe@unibas.ch) |
| Inhalt | This course will describe the components of the translational apparatus and their putative roles in each of the three steps of protein synthesis: initiation, elongation, and termination. The first part of the course will draw information from the current literature to cover specific cases of translational control. The translational control section will cover a wide spectrum of topics including frame shifting, attenuation, phosphorylation, and transformation. The second part of the course will emphasize the role of translational control in the regulation of cell growth, with particular emphasis on the TOR signaling network. Once synthesized, proteins often require posttranslational modifications either to achieve their full biological activity or to regulate their activity. In these lectures we will discuss the various forms of posttranslational modifications of proteins and the consequences of these modifications for protein function. The lectures will give an up-to-date overview of protein splicing, poly-protein processing, different forms of modifications of amino acids, protein folding and protein transport phenomena requiring proteolysis. |
| Weblink | http://www.biozentrum.unibas.ch/educatio |
| Unterrichtssprache | Englisch |
| Einsatz digitaler Medien | kein spezifischer Einsatz |
| Intervall | Wochentag | Zeit | Raum |
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Keine Einzeltermine verfügbar, bitte informieren Sie sich direkt bei den Dozierenden.
| Module |
Cycle G: Gene Expression and Epigenetics (Promotionsfach: Biochemie) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Biophysik) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Genetik) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Mikrobiologie) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Zellbiologie) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Pharmakologie) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Neurobiologie) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Bioinformatik) Cycle G: Gene Expression and Epigenetics (Promotionsfach: Strukturbiologie) Cycle G: Gene Expression and Epigenetics (Master Molekularbiologie) Modul Vertiefungsfach Molekularbiologie (Master Nanowissenschaften) |
| Prüfung | Lehrveranst.-begleitend |
| An-/Abmeldung zur Prüfung | Anmelden: Belegen; Abmelden: Dozierende |
| Wiederholungsprüfung | keine Wiederholungsprüfung |
| Skala | Pass / Fail |
| Belegen bei Nichtbestehen | beliebig wiederholbar |
| Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
| Anbietende Organisationseinheit | Departement Biozentrum |