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14429-01 - Vorlesung: Development of Therapeutic Antibodies (1 KP)
| Semester | Herbstsemester 2017 |
| Angebotsmuster | Jedes Herbstsemester |
| Dozierende |
Hermann Gram (hermann.gram@unibas.ch)
Steffen Hartmann (steffen.hartmann@unibas.ch) Thomas Huber (thomas.huber@unibas.ch) Frank Kolbinger (frank.kolbinger@unibas.ch) Roland Preston (roland.preston@unibas.ch) Daniel Ricklin (d.ricklin@unibas.ch, BeurteilerIn) Maximilian Woisetschläger (maximilian.woisetschlaeger@unibas.ch) |
| Inhalt | Therapeutic antibodies have evolved into a highly important and rapidly growing sector of modern drug therapy, with several antibody-based drugs being available to the clinic and many more in clinical development. In this lecture series, experts from pharmaceutical industry with broad experience in antibody development will guide through the various aspects of bringing a therapeutic antibody from discovery to the clinic. In particular, the lectures will cover the following topics: - Structure and characteristics of immunoglobulins, and generation of monoclonal antibodies - Effector functions and pharmacokinetic properties of antibodies - Preclinical development, characterization and production of therapeutic antibodies - Clinical development and therapeutic use of antibody-based therapeutics - Examples and case studies of therapeutic antibodies in the clinic - Emerging trends in the discovery and development of antibody-based drugs As part of the lecture series, we will also organize a guided tour at one of Novartis’ antibody facilities (see special announcement). |
| Lernziele | During this lecture series, the students will learn about: - the key structural, functional and pharmaceutical features of antibodies - established and emerging strategies to design antibody-based drugs - options to produce antibodies at the laboratory or industrial scale - considerations and examples of using therapeutic antibodies in the clinic |
| Bemerkungen | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated) |
| Weblink | ADAM |
| Unterrichtssprache | Englisch |
| Einsatz digitaler Medien | kein spezifischer Einsatz |
| Intervall | Wochentag | Zeit | Raum |
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Keine Einzeltermine verfügbar, bitte informieren Sie sich direkt bei den Dozierenden.
| Module |
Modul Target Identification/Validation to Discovery of Modulators (Master Drug Sciences) Vertiefungsmodul Biologicals / Biogene Verbindungen (Master Pharmazeutische Wissenschaften (Studienbeginn vor 01.08.2016)) Wahlbereich Master Pharmazie: Empfehlungen (Master Pharmazie) |
| Prüfung | Lehrveranst.-begleitend |
| Hinweise zur Prüfung | Electronic written examination at the end of the semester (60 min, iPad) http://pharma.unibas.ch/teaching/leistungsueberpruefungen/lluep |
| An-/Abmeldung zur Prüfung | Anm.: Belegen Lehrveranstaltung; Abm.: stornieren |
| Wiederholungsprüfung | keine Wiederholungsprüfung |
| Skala | 1-6 0,5 |
| Belegen bei Nichtbestehen | beliebig wiederholbar |
| Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
| Anbietende Organisationseinheit | Departement Pharmazeutische Wissenschaften |