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48335-01 - Vorlesung: Biomolecular nanotechnology (3 KP)
| Semester | Herbstsemester 2021 |
| Angebotsmuster | unregelmässig |
| Dozierende |
Isabel Kolinko (isabel.kolinko@unibas.ch)
Michael Nash (michael.nash@unibas.ch, BeurteilerIn) |
| Inhalt | Introduction to biomacromolecules; Measurement techniques for characterisation of biomacromolecules; Fundamentals of molecular recognition; Recombinant DNA; Protein engineering; Directed evolution; Protein folding; Polymers; Elastin-like polypeptides; Intelligent materials; Spatially localized hydrogels; Mechanical properties of proteins and macromolecules; Single-molecule force spectroscopy. |
| Lernziele | The objective is to familiarise the students with a broad range of topics related to biotechnology, nanotechnology, and biophysics with a focus on current research and reading of scientific literature. |
| Literatur | (1) Alberts, Molecular Biology (Ch.2 Cellular chemistry). (2) Ratner, Biomaterials Science (Ch. 2.3, 2.4 Polymers & hydrogels). (3) Walsh, Protein Biochemistry, (Ch. 2, Protein Structure). (4) Nath et. al. Analytical chemistry, 74(3): 504-509, 2002. (5) DeMonte, D., et. al. Proteins DOI: 10.1002/prot.24320, 2013. (6) Feldhaus, M.J., et al. Nature Biotechnology 21 (2): 163–70, 2003. (7) Link, A.J., et al. PNAS 103 (27): 10180–85, 2006. (8) Chen, I. et al. PNAS 108 (28): 11399–404, 2011. (9) Marín-Navarro, J., et. al. PloS One 10 (12). journals.plos.org: e0144289, 2015. (10) Christensen, T. et al. Biomacromolecules 14 (5): 1514–19, 2013. (11) Shimoboji, T., et al. PNAS. 99(26): 16592-16596, 2002. (12) Puchner, E.M. et al. PNAS. 105(36): 13385–13390, 2008. (13) Dietz, H., et al. PNAS 103 (5): 1244–47, 2006. |
| Bemerkungen | Access to Rosental only via gate BPR 1047, Mattenstrasse 24a. Students of the University of Basel register on MOnA for an access to the Rosental please until September 14th, 2021. ETH-students need to apply for a badge in advance with an email to: student-admin@bsse.ethz.ch prior the start of the lecture. |
| Anmeldung zur Lehrveranstaltung | Register on MOnA. |
| Unterrichtssprache | Englisch |
| Einsatz digitaler Medien | kein spezifischer Einsatz |
| Intervall | Wochentag | Zeit | Raum |
|---|---|---|---|
| wöchentlich | Mittwoch | 08.00-10.00 | Campus Rosental 1095, Seminarraum O02.017 |
| wöchentlich | Donnerstag | 08.00-09.00 | Campus Rosental 1060, Sitzungsraum 2.14 |
Einzeltermine
| Module |
Doktorat Chemie: Empfehlungen (Promotionsfach: Chemie) Modul: Physical Chemistry (Masterstudium: Chemie) Modul: Vertiefung Chemie (Masterstudium: Nanowissenschaften) Modul: Vertiefung Molekularbiologie (Masterstudium: Nanowissenschaften) |
| Prüfung | Lehrveranst.-begleitend |
| Hinweise zur Prüfung | Weekly discussion of reading assignments; in-class presentation; oral exam |
| An-/Abmeldung zur Prüfung | Anm.: Belegen Lehrveranstaltung; Abm.: stornieren |
| Wiederholungsprüfung | keine Wiederholungsprüfung |
| Skala | 1-6 0,5 |
| Belegen bei Nichtbestehen | beliebig wiederholbar |
| Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
| Anbietende Organisationseinheit | Departement Chemie |