Zurück zur Auswahl
29954-01 - Vorlesung: Food Toxicology and Risk Assessment (1 KP)
| Semester | Frühjahrsemester 2025 |
| Angebotsmuster | Jedes Frühjahrsem. |
| Dozierende | Hanspeter Nägeli (h.naegeli@unibas.ch, BeurteilerIn) |
| Inhalt | This lecture presents the current state of the science of risk assessment of chemicals (additives, pesticide or drug residues, phytochemicals, toxins and contaminants) in food by consideration of the four stages of risk assessment, i.e., hazard identification, hazard characterization, exposure assessment and risk characterization. The contribution of animal-based methods and pharmacologic or epidemiologic studies will be outlined with emphasis on the importance of first applying existing chemical, biochemical, physiologic or toxicological knowledge. The lecture will also discuss the issues of risk management and communication in food toxicology, identify gaps of knowledge and outline areas of current research. Specific topics: Introduction – Historical background, legal basis, acute threats and pervasive low-level exposures Tools of risk assessment and management – NOEL, ADI/TDI, BMD & MOE concepts, examples of MLs & MRLs Residue toxicology – Pesticides & veterinary drugs Analytical guidelines – screening & confirmatory methods, interpretation of results The concept of “threshold of toxicological concern” with reference to food Carcinogens in food (including toxicants induced during food processing) Toxicologic assessment of genetically modified food Anthropogenic contaminants – POPs, heavy metals Phytochemicals in food Mycotoxins in food Dietary chemoprotection Emerging issues in food toxicology – Case studies |
| Lernziele | Understand methods of risk assessment of chemicals in food, application to current issues in food toxicology, knowledge of major food-borne chemical hazards |
| Literatur | Watson DH (2004) Pesticide, veterinary and other residues in food. Woodhead Publishing, CRC Prss, Boca Raton Different opinions published by EFSA (European Food Safety Authority) |
| Bemerkungen | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated |
| Weblink | Department of Pharmaceutical Sciences |
| Teilnahmevoraussetzungen | Completed Bachelor degree |
| Unterrichtssprache | Englisch |
| Einsatz digitaler Medien | kein spezifischer Einsatz |
| Intervall | Wochentag | Zeit | Raum |
|---|---|---|---|
| wöchentlich | Dienstag | 10.15-12.00 | Biozentrum, Hörsaal U1.101 |
Einzeltermine
| Datum | Zeit | Raum |
|---|---|---|
| Dienstag 18.02.2025 | 10.15-12.00 Uhr | Biozentrum, Hörsaal U1.101 |
| Dienstag 25.02.2025 | 10.15-12.00 Uhr | Biozentrum, Hörsaal U1.101 |
| Dienstag 04.03.2025 | 10.15-12.00 Uhr | Biozentrum, Hörsaal U1.101 |
| Dienstag 11.03.2025 | 10.15-12.00 Uhr | Fasnachstferien |
| Dienstag 18.03.2025 | 10.15-12.00 Uhr | Biozentrum, Hörsaal U1.101 |
| Dienstag 25.03.2025 | 10.15-12.00 Uhr | Biozentrum, Hörsaal U1.101 |
| Dienstag 01.04.2025 | 10.15-12.00 Uhr | Biozentrum, Hörsaal U1.101 |
| Dienstag 08.04.2025 | 10.15-12.00 Uhr | Biozentrum, Hörsaal U1.101 |
| Montag 14.04.2025 | 13.45-14.45 Uhr | Biozentrum, Hörsaal U1.131 |
| Module |
Wahlbereich Master Drug Sciences: Empfehlungen (Masterstudium: Drug Sciences) Wahlbereich Master Pharmazie: Empfehlungen (Masterstudium: Pharmazie) |
| Prüfung | Lehrveranst.-begleitend |
| Hinweise zur Prüfung | Please refer to the list: https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
| An-/Abmeldung zur Prüfung | Anm.: Belegen Lehrveranstaltung; Abm.: stornieren |
| Wiederholungsprüfung | keine Wiederholungsprüfung |
| Skala | 1-6 0,5 |
| Belegen bei Nichtbestehen | beliebig wiederholbar |
| Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
| Anbietende Organisationseinheit | Departement Pharmazeutische Wissenschaften |