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46375-01 - Vorlesung: From Novel Targets to Novel Therapeutic Modalities (2 KP)
| Semester | Frühjahrsemester 2025 |
| Angebotsmuster | Jedes Frühjahrsem. |
| Dozierende | Adrian Roth (adrian.roth@unibas.ch) |
| Inhalt | 1. Introduction to the lecture series: From Novel Targets to Novel Therapeutic Modalities 2. Modern Drug Development starts with the Patient: Making use of "Real World Data" 3. Nucleic Acid based Therapeutics: from RNAi to Antisense Oligos 4. Development of Antisense Oligonucleotide Drugs 5. Small Molecule Drug Discovery: A Journey Through the Rule of 5 Space and Beyond 6. Mechanistic, Statistical and Causal Modelling in Drug Discovery 7. Gene and cell therapies 8. From Monoclonal Antibodies to engineeered Bi-Specifics 9. New Treatment Avenues: Personalized Healthcare and Understanding Individual Drivers of Response |
| Lernziele | Know the basics on nucleic acid based therapeutics and understand the issues relevant for the development of antisense oligonucleotide drugs. Know the basics about monoclonal antibodies used as drugs. Understand issues relevant to classic and new small molecules as well as peptide drugs. Know the basics of gene and stem cell therapies. Know the basics of patenting of drug modalities. |
| Literatur | Review Articles that will be distributed during the lectures |
| Bemerkungen | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated |
| Weblink | Department of Pharmaceutical Sciences |
| Teilnahmevoraussetzungen | Completed Bachelor degree |
| Unterrichtssprache | Englisch |
| Einsatz digitaler Medien | kein spezifischer Einsatz |
| Intervall | Wochentag | Zeit | Raum |
|---|---|---|---|
| wöchentlich | Donnerstag | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
Einzeltermine
| Datum | Zeit | Raum |
|---|---|---|
| Donnerstag 20.02.2025 | 08.15-12.00 Uhr | Pharmazentrum, Hörsaal 2 |
| Donnerstag 27.02.2025 | 08.15-12.00 Uhr | Pharmazentrum, Hörsaal 2 |
| Donnerstag 06.03.2025 | 08.15-12.00 Uhr | Pharmazentrum, Hörsaal 2 |
| Donnerstag 13.03.2025 | 08.15-12.00 Uhr | Fasnachstferien |
| Donnerstag 20.03.2025 | 08.15-12.00 Uhr | Pharmazentrum, Hörsaal 2 |
| Donnerstag 27.03.2025 | 08.15-12.00 Uhr | Pharmazentrum, Hörsaal 2 |
| Donnerstag 03.04.2025 | 08.15-12.00 Uhr | Pharmazentrum, Hörsaal 2 |
| Donnerstag 10.04.2025 | 08.15-12.00 Uhr | Pharmazentrum, Hörsaal 2 |
| Dienstag 15.04.2025 | 08.45-09.45 Uhr | Biozentrum, Hörsaal U1.101 |
| Module |
Modul: Target Identification/Validation to Discovery of Modulators (Masterstudium: Drug Sciences) Modul: Vertiefung Medizinische Nanowissenschaften (Masterstudium: Nanowissenschaften) Wahlbereich Master Pharmazie: Empfehlungen (Masterstudium: Pharmazie) |
| Prüfung | Lehrveranst.-begleitend |
| Hinweise zur Prüfung | Refert to the list at https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
| An-/Abmeldung zur Prüfung | Anm.: Belegen Lehrveranstaltung; Abm.: stornieren |
| Wiederholungsprüfung | keine Wiederholungsprüfung |
| Skala | 1-6 0,5 |
| Belegen bei Nichtbestehen | beliebig wiederholbar |
| Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
| Anbietende Organisationseinheit | Departement Pharmazeutische Wissenschaften |