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55001-01 - Vorlesung: Biocatalysis for Organic Synthesis (3 KP)
| Semester | Herbstsemester 2025 |
| Angebotsmuster | unregelmässig |
| Dozierende | Valentin Köhler (valentin.koehler@unibas.ch, BeurteilerIn) |
| Inhalt | The main objective is to discuss enzyme catalysis for fine chemical synthesis and includes the following chapters: general aspects of enzyme catalysis, hydrolytic reactions, reductions, oxidations, formation of C-C bonds, addition and elimination, transfer reactions, halogenation and dehalogenation. Mechanisms, stereochemistry, cascade catalysis, directed evolution, enzyme repurposing, process considerations, and other topics will also be addressed. |
| Lernziele | The primary aim is to learn the central transformations frequently employed in biotransformations and apply this knowledge to synthesis planning for simple molecules. |
| Literatur | The foundation of the lecture is the book ‘Biotransformations in Organic Chemistry, 7th edition’ by Kurt Faber, available on the University net. An additional resource is the book ‘Biocatalysis in Organic Synthesis’ by Nicholas J. Turner and Luke Humphreys. Research articles contribute to the lecture content. |
| Bemerkungen | For the timely organization of the access to the Rosental campus, students of the University of Basel must register on services.unibas.ch until September 8th, 2025. Access to building BPR-1060 via gate 1047 only, the UniCard must be presented upon entry. |
| Anmeldung zur Lehrveranstaltung | Register on services.unibas.ch For the timely organization of the access to the Rosental campus, students of the University of Basel must register on services.unibas.ch until September 8th, 2025. Access to building BPR-1060 via gate 1047 only, the UniCard must be presented upon entry. |
| Unterrichtssprache | Englisch |
| Einsatz digitaler Medien | kein spezifischer Einsatz |
| Intervall | Wochentag | Zeit | Raum |
|---|---|---|---|
| wöchentlich | Montag | 13.15-15.00 | Chemie, Organische, Kleiner Hörsaal OC |
| wöchentlich | Dienstag | 09.15-10.00 | Campus Rosental 1060, Seminarraum 7.48 |
Einzeltermine
| Module |
Doktorat Chemie: Empfehlungen (Promotionsfach: Chemie) Modul: Mixed Topics (Masterstudium: Chemie) Modul: Organische Synthese (Bachelorstudium: Chemie) Modul: Vertiefung Chemie (Masterstudium: Nanowissenschaften) |
| Prüfung | Lehrveranst.-begleitend |
| Hinweise zur Prüfung | Presentation of a recent research article and written exam at the end of the course. |
| An-/Abmeldung zur Prüfung | Anm.: Belegen Lehrveranstaltung; Abm.: stornieren |
| Wiederholungsprüfung | keine Wiederholungsprüfung |
| Skala | 1-6 0,5 |
| Belegen bei Nichtbestehen | beliebig wiederholbar |
| Zuständige Fakultät | Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch |
| Anbietende Organisationseinheit | Departement Chemie |