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13186-01 - Lecture: G3: Structure, Processing and Function of RNA (2 CP)
| Semester | fall semester 2012 |
| Course frequency | Every 2nd fall sem. |
| Lecturers |
Marc Bühler (marc.buehler@unibas.ch, Assessor)
Rafal Ciosk (RAFAL.CIOSK@UNIBAS.CH) Helge Grosshans (helge.grosshans@unibas.ch) |
| Content | The discovery that RNA is not only a carrier of genetic information or a structural scaffold in ribonucleoprotein particles but can also act as a catalyst in many different cellular processes, greatly stimulated research on the structure, processing and function of RNA. The lecture will cover the following topics: chemistry and structure of RNA; major classes of cellular RNAs (mRNAs, tRNAs, rRNAs, snRNAs, and the newly discovered small regulatory ~20-nt RNAs); chemistry and structure of RNA; pre-mRNA processing with emphasis on splicing and polyadenylation; biogenesis of tRNA and rRNA; biochemistry and function of RNA interference (RNAi) and microRNAs; RNA trafficking in the cell, RNA quality control and RNA degradation; and regulated mRNA translation during development. Also covered are RNA-protein interactions and major classes of ribonucleoprotein particles and the evolution of RNAs. |
| Weblink | http://www.biozentrum.unibas.ch/graduate |
| Language of instruction | English |
| Use of digital media | Online, optional |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Cycle G: Molecular Biology (PhD subject: Biochemistry) Cycle G: Molecular Biology (PhD subject: Biophysics) Cycle G: Molecular Biology (PhD subject: Genetics) Cycle G: Molecular Biology (PhD subject: Microbiology) Cycle G: Molecular Biology (PhD subject: Cell Biology) Cycle G: Molecular Biology (PhD subject: Pharmacology) Cycle G: Molecular Biology (PhD subject: Neurobiology) Cycle G: Molecular Biology (PhD subject: Bioinformatics) Cycle G: Molecular Biology (PhD subject: Structural Biology) Cycle G: Molecular Biology (Master Molecular Biology) Module Specialisation: Molecular Biology (Master Nanosciences) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg.: course registration; dereg.: teaching staff |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Biozentrum |