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41225-01 - Vorlesung: Bioinorganic chemistry (2 KP)

Semester Herbstsemester 2015
Course frequency unregelmässig
Lecturers Thomas R. Ward (thomas.ward@unibas.ch, Assessor)
Content Basics of protein structure
Metal cofactors and their interactio with proteins
Metals in medicine
Analysis of key metalloenzymes including
Hydrolases, Oxygenases, Oxidases, Hydrogenases, Transport proteins, DNA-binding proteins etc.
Energy-related challenges: The solution is bio-inorganic
Selected topics from current literature
Learning objectives Identify key features of metalloenzymes and enzyme mimics.
Deduce and draw reasonable reaction mechanisms of metalloenzymes.
Understand the role of metalloenzyme in solving energy-related grand challenges.
Propose realistic enzyme mimics
Bibliography Principles of Bioinorganic Chemistry, 1994, Stephen J. Lippard, Jeremy M. Berg, University Science Books
Biological Inorganic Chemistry: Structure and Reactivity, 2nd Ed. 2007, H. B. Gray et al., University Science Books
Various up-to-date review articles from Chem. Rev., Chem. Soc. Rev., Angew. Chem. and Acc. Chem. Res.
Weblink structure of metalloenzymes made easy

 

Admission requirements Bachelor in chemistry with a solid background in organometallic and coordination chemistry
Basic knowledge in biochemistry is an asset
Course application Belegen via MOnA.
Language of instruction Englisch
Use of digital media Online-Angebot fakultativ

 

Interval Weekday Time Room

No dates available. Please contact the lecturer.

Modules Doktorat Chemie: Empfehlungen (Promotionsfach: Chemie)
Modul Vertiefungsfach Chemie (Master Nanowissenschaften)
Vertiefungsmodul (Master Chemie)
Assessment format Lehrveranst.-begleitend
Assessment details One hour written examination
Assessment registration/deregistration Anmelden: Belegen; Abmelden: Dozierende
Repeat examination keine Wiederholungsprüfung
Scale 1-6 0,5
Repeated registration beliebig wiederholbar
Responsible faculty Philosophisch-Naturwissenschaftliche Fakultät, studiendekanat-philnat@unibas.ch
Offered by Departement Chemie

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