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48186-01 - Lecture: Laser and Optics in Medicine (6 CP)
| Semester | spring semester 2019 |
| Course frequency | Every spring sem. |
| Lecturers |
Ferda Canbaz (ferda.canbaz@unibas.ch)
Azhar Zam (azhar.zam@unibas.ch, Assessor) |
| Content | Introduction: Nature of light, fundamentals of light-matter interactions, photobiology, photophysics, photochemistry, laser and light sources, laser safety. Light-Tissue Interactions: Photochemical interaction, biostimulation, photo-thermal effects, photoablation, plasma-induced ablation, photo-acoustic effects, photon transport, monte carlo simulations, adding doubling method. Spectroscopy: Absorption, diffuse reflectance, fluorescence, Raman and tissue spectroscopy Biosensors: Principles of optical biosensing, optical geometries for biosensors and biosensing methods. Bioimaging Principles and Techniques: Introduction to optical microscopy, principle of image formation, amplitude and phase microscopy, polarization, fluorescence and confocal microscopy, optical diffraction tomography and new microscopic techniques. 2D Bioimaging: Endoscopy, videomicroscopy, diffuse reflectance, laser Doppler perfusion imaging, laser speckle perfusion imaging, . 3D Bioimaging: Optical coherence tomography, polarimetry, diffuse optical tomography, photothermal imaging, photoacoustic imaging and optical biopsy. Applications Laser and Optics in Medicine and Biology: Biophotonics applications in medicine, laser tweezers and scissors, microarray and microfluidic technologies for genomics and proteomics, flow cytometry, bioluminescence, bio-nanophotonics, opto-genetics, tissue engineering with light and data analysis in Biophotonics. |
| Bibliography | Recommended Reading: Prasad, P.N., “Introduction to Biophotonics”, (Wiley-VCH), 2003 Wang, LV and Wu HI, Biomedical Optics, Principles and Imaging, (Wiley-VCH), 2007, Demchenko, A P "Introduction to Fluorescence Sensing", Springer, 2008 Popp,Tuchin, Chiou, Heinemann (Editors) Handbook of Biophotonics, 3 Volume Set, (Wiley-VCH), 2012. Leahy, M.J. editor, Microcirculation Imaging, (Wiley-VCH), 2012. |
| Comments | There will be no lecture on March 13th, 2019. There will be 2x practical works during this course. |
| Weblink | DBE |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Doctorate Biomedical Engineering: Recommendations (PhD subject: Biomedical Engineering) Module: Biomaterials Science and Nanotechnology (Master's Studies: Biomedical Engineering) Module: Image-Guided Therapy (Master's Studies: Biomedical Engineering) |
| Assessment format | record of achievement |
| Assessment details | Attendance 25%, Practical Work 20%, Quiz 15% and Final oral Exam 40%. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | one repetition, best attempt counts |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Medicine |
| Offered by | Departement Biomedical Engineering (DBE) |