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44812-01 - Lecture: Mechanisms of Toxicity (1 CP)
| Semester | fall semester 2020 |
| Course frequency | Every fall sem. |
| Lecturers | Stephan Krähenbühl (stephan.kraehenbuehl@unibas.ch) |
| Content | The following mechanisms will be discussed: general principles of interaction with cells and proteins, repair mechanisms, mitochondrial respiratory chain, uncoupling, mitochondrial DNA, mitochondrial fatty acid oxidation. ER stress response, redox reactions, Lysosomes, phospholipidosis, cytokines, inflammasome, apoptosis, necrosis, nuclear receptors, ion homeostasis |
| Learning objectives | Students should know the principle toxicological mechanisms how toxicants can damage cell organelles and cells. |
| Bibliography | Klaassen CD, Casarett and Doull's Essentials of Toxicology. McGraw-Hill. Newest edition. Klaassen CD. Casarett and Doull's Toxicology, the basic Science of Poisons. McGraw-Hill. Newest edition. |
| Comments | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated) |
| Admission requirements | Completed Bachelor degree |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
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No dates available. Please contact the lecturer.
| Modules |
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy) Module: Translating Pharmacology and Drug Safety to Humans (Master's Studies: Drug Sciences) |
| Assessment format | continuous assessment |
| Assessment details | refer to this link:https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |