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53273-01 - Lecture: Testing drugs - a glimpse into analytical chemistry (3 CP)
| Semester | spring semester 2023 |
| Course frequency | Irregular |
| Lecturers |
Samuel Lorenz Bader (samuellorenz.bader@unibas.ch)
Christian Bauer (christian.bauer@unibas.ch) Balázs Bobály (balazs.bobaly@unibas.ch) Gisela Helene Fontaine (giselahelene.fontaine@unibas.ch) Rolf Hilfiker (rolf.hilfiker@unibas.ch) Oliver Höcker (oliver.hoecker@unibas.ch) Steffen Kiessig (steffen.kiessig@unibas.ch) Marius Koch (ma.koch@unibas.ch) Bernd Moritz (bernd.moritz@unibas.ch) Maria Anna Schwarz (maria.schwarz@unibas.ch, Assessor) |
| Content | Introduction and overview of analytical techniques used in pharmaceutical industry; differentiation between molecule categories, Q-standards, development process, validation Basics of solid forms (salts, co-crystals, polymorphs) and selected methods to characterize solids (XRPD, DSC, TG, Raman) Inorganic trace element analysis AAS (flame, graphite furnace, cold vapour, hydride generation), ICP-OES, ICP-MS, Sample preparation, Applications in pharmaceutical analysis Mass spectrometry 1 (Instrumentation, Spectra, Small molecule applications) Mass spectrometry 2 (Peptide mapping and applications) Mass spectrometry 3 (Protein molecular weight measurement and applications) CE basics and applications of proteins (GCE, cIEF, CZE) and CE applications of BioPharm (deamidation, pegylation, ACE, chiral,….) LC techniques applied for small and large molecules Spectroscopic methods Posttranslational modifications of proteins (general overview), a deeper insight into the analysis of glycans (CE, HPLC, MS) |
| Course application | https://services.unibas.ch |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Course auditors welcome |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Thursday | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
Dates
| Date | Time | Room |
|---|---|---|
| Thursday 23.02.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 02.03.2023 | 14.30-17.15 | Fasnachstferien |
| Thursday 09.03.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 16.03.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 23.03.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 30.03.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 06.04.2023 | 14.30-17.15 | Ostern |
| Thursday 13.04.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 20.04.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 27.04.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 04.05.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 11.05.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 18.05.2023 | 14.30-17.15 | Auffahrt |
| Thursday 25.05.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Thursday 01.06.2023 | 14.30-17.15 | Chemie, Organische, Kleiner Hörsaal OC |
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module: Mixed Topics (Master's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |