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50310-01 - Lecture with practical courses: Analytical Applications in Drug Discovery (1 CP)
| Semester | spring semester 2025 |
| Course frequency | Every spring sem. |
| Lecturers | Stephan Müller (stephan.mueller@unibas.ch, Assessor) |
| Content | Examples for typical topics (subject to change): Introduction and toolbox: What to find where. Suppliers, literature, information, software Advanced HPLC methods: UPLC, column materials, column switching Application quantitative Bioanalysis; HPLC-UV Method validation example Advanced mass spectrometry: accurate mass and elemental composition; application in qualitative analysis Advanced MS/MS experiments, data dependent analysis, ion mobility; application in chemical, biochemical and -omics analysis noncovalent interaction analysis; application in binding assays Application Biomarker Analysis; LC/MS-MS |
| Learning objectives | Insight and beginner's experience of analytical practise in research: You know material and information sources and providers, you can search, manage and extract literature on practical examples and derive a proposal for method development. You can use Excel for the evaluation of typical amounts of data and have to do some troubleshooting. You learn some more on advanced instrumental analytics, especially mass spectrometry. |
| Bibliography | on unibas.smv3.ch download page or ADAM |
| Weblink | Participants webpage, please register |
| Admission requirements | Completed Bachelor degree, STRONGLY RECOMMENDED Analytik VI in Basel (46378-01). Good Excel skills (use of formulae for simple statistical functions) Beside the usual booking over MonA registration under unibas.smv3.ch is needed! Laptop with power supply for 2h during the lessons Recent MS Office software or equivalent Standard web browser (Safari, Firefox, Chrome, MSE) Structure Editor: Download and install ChemAxon's Marvin suite for structure design. Scientific calculator |
| Course application | 1. University booking (Belegen) as usual over MoNa 2. Register at unibas.smv3.ch to access the software and material download |
| Language of instruction | English |
| Use of digital media | Online, mandatory |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Tuesday | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
Dates
| Date | Time | Room |
|---|---|---|
| Tuesday 18.02.2025 | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 25.02.2025 | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 04.03.2025 | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 11.03.2025 | 15.15-17.00 | Fasnachstferien |
| Tuesday 18.03.2025 | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 25.03.2025 | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 01.04.2025 | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 08.04.2025 | 15.15-17.00 | Pharmazentrum, Hörsaal 2 |
| Modules |
Electives Master Drug Sciences: Recommendations (Master's Studies: Drug Sciences) Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy) |
| Assessment format | continuous assessment |
| Assessment details | The QA will take place in form of exercises or online or paper quizzes during the lessons. The tasks will require informatics tools and internet access. Therefore, registration at unibas.smv3.ch and a PC/Mac with web access and MS Office during the lessons is mandatory. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |