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29957-01 - Lecture: Psychopharmacology and Neurotoxicology (1 CP)

Semester spring semester 2025
Course frequency Every spring sem.
Lecturers Amandine Grimm (amandine.grimm@unibas.ch)
Hallam Gugelmann (hallam.gugelmann@unibas.ch)
Martin Hardmeier (martin.hardmeier@unibas.ch)
Matthias Emanuel Liechti (matthias.liechti@unibas.ch)
Dino Lüthi (dino.luethi@unibas.ch, Assessor)
Deborah Rudin (deborah.rudin@unibas.ch)
Content Schedule may change (see on ADAM)
Week 1: Introduction and overview (D. Rudin; D. Lüthi)
Week 2: Fast-acting neurotoxins (H. Gugelmann); Monoamine system (D. Rudin; D. Lüthi)
Week 3: Endocannabinoid system (H. Gugelmann)
Week 4: Cholinergic system; GABA and glutamatergic system (D. Rudin; D. Lüthi)
Week 5: Neurotoxic viruses and warfare agents (H. Gugelmann); Cellular assays (A. Grimm)
Week 6: Neurological evaluation (M. Hardmeier); Mitochondrial toxicity (A. Grimm)
Week 7: Self-study
MC exam (on a separate date to be announced)
Learning objectives -To understand how chemicals and drugs interact with neuronal structures and functions.
-Ability to evaluate example cases.
Bibliography Lecture slides on ADAM.
Further reading:
Klaassen, Casaretts & Dull’s, Toxicology, The basis science of poisons, Chapter: Toxic responses of the nervous system.
Goodman & Gilman’s, Manual of Pharmacology and Therapeutics, paperback, McGraw Hill Medical, (available as small paper back or full hard cover book)
a. Chapter 6-11: Drugs acting at synaptic and neuroeffector junctional sites
b. Chapter 12-23: Drugs acting on the central nervous system and neurotransmission in the CNS
Comments Film and sound recordings during the course are strictly forbidden (recorders may be confiscated)
Weblink Department of Pharmaceutical Sciences

 

Admission requirements Completed Bachelor degree
Language of instruction English
Use of digital media No specific media used

 

Interval Weekday Time Room
wöchentlich Wednesday 08.15-10.00 Pharmazentrum, Hörsaal 2

Dates

Date Time Room
Wednesday 19.02.2025 08.15-10.00 Pharmazentrum, Hörsaal 2
Wednesday 26.02.2025 08.15-10.00 Pharmazentrum, Hörsaal 2
Wednesday 05.03.2025 08.15-10.00 Pharmazentrum, Hörsaal 2
Wednesday 12.03.2025 08.15-10.00 Fasnachstferien
Wednesday 19.03.2025 08.15-10.00 Pharmazentrum, Hörsaal 2
Wednesday 26.03.2025 08.15-10.00 Pharmazentrum, Hörsaal 2
Wednesday 02.04.2025 08.15-10.00 Pharmazentrum, Hörsaal 2
Wednesday 09.04.2025 08.15-10.00 Pharmazentrum, Hörsaal 2
Wednesday 16.04.2025 11.00-12.00 Biozentrum, Hörsaal U1.101
Modules Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy)
Module Specialisation: Medical Nanosciences (Master's Studies: Nanosciences)
Module: Translating Pharmacology and Drug Safety to Humans (Master's Studies: Drug Sciences)
Assessment format continuous assessment
Assessment details Please refert to the list:
https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/
Assessment registration/deregistration Reg.: course registration, dereg: cancel course registration
Repeat examination no repeat examination
Scale 1-6 0,5
Repeated registration as often as necessary
Responsible faculty Faculty of Science, studiendekanat-philnat@unibas.ch
Offered by Departement Pharmazeutische Wissenschaften

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