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67493-01 - Lecture: Neglected Tropical Disease: From Genes to Elimination (1 CP)
| Semester | spring semester 2025 |
| Course frequency | Every spring sem. |
| Lecturers |
Peter Odermatt (peter.odermatt@unibas.ch, Assessor)
Somphou Sayasone (somphou.sayasone@unibas.ch) |
| Content | Asian liver fluke infections, Opisthorchis viverrini and Clonorchis sinensis, are human neglected trematode infections with a complex life cycle (two intermediate: freshwater snails, cyprinoid fish species), several definitive host besides humans (cat, dogs, wildlife). ALF is a trematode infection of the biliary tract and has considerable impact on infected individuals and the affected societies. Its complex life cycles makes the control challenging. Divers research approaches are employed to improve diagnosis, treatment and sustainably control the infection in the population and manage the disease, including cancer, in patients. Content: • Lectures on the biology, clinical significance, diagnosis, and epidemiology of parasitic infections and control approaches; • Lectures on the interaction between host-pathogen-environment and the dynamic transmission of Ov • Lectures on severe clinical aspects associated with Ov infections and their adequate and appropriate treatment and care at different stage; • Lectures on biomarkers to assess early hepato-biliary morbidities associated with Ov infection that may be beneficial in curative treatment; • Demonstrations of the role of multi-disciplinarity and the one-health approach in effective intervention; • Demonstrations at the microscope, virtual field visits in Asia over zoom |
| Learning objectives | The course uses Asian liver fluke (ALF) infection, a neglected tropical disease, as an example of a complex infectious disease to demonstrate research and public health approaches required to create the knowledge-base to control and potentially eliminate this neglected tropical disease. After the course, participants will be able to (i) identify the key features of ALF life cycles, transmission dynamics and morbidity development; (ii) the multi- and transdisciplinary research approaches required to generate essential knowledge to comprehensively control Asian liver fluke (ALF) infection and morbidity in individuals and populations in the endemic settings. In particular, the participants will understand what research approaches are essential to assess the infection and morbidity burden of the ALF infections, the key features of the local settings, the ecology of intermediate hosts; the mechanisms and pathways of morbidity development; the dynamics of transmission and development of morbidity; and the impact of control measures. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| 14-täglich | Tuesday | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
Dates
| Date | Time | Room |
|---|---|---|
| Tuesday 18.02.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 25.02.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 04.03.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 11.03.2025 | 09.15-11.00 | Fasnachstferien |
| Tuesday 18.03.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 25.03.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 01.04.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 08.04.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 15.04.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 22.04.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 29.04.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 06.05.2025 | 08.15-10.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 13.05.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 20.05.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Tuesday 27.05.2025 | 09.15-11.00 | Swiss TPH Neubau, Seminarraum 4 |
| Modules |
Module: Advances in Epidemiology, Statistics and Global & Public Health (Master's Studies: Epidemiology) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Schweizerisches Tropen- und Public Health-Institut |