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48186-01 - Lecture: Laser and Optics in Medicine (3 CP)
| Semester | spring semester 2025 |
| Course frequency | Every spring sem. |
| Lecturers |
Dunia Beatriz Blaser (dunia.blaser@unibas.ch)
Ferda Canbaz (ferda.canbaz@unibas.ch, Assessor) Christian Haas (ch.haas@unibas.ch) Arsham Hamidi (arsham.hamidi@unibas.ch) |
| Content | Introduction: Nature of light, fundamentals of light-matter interactions, photobiology, photophysics, photochemistry, laser and light sources. Light-Tissue Interactions: Photochemical interaction, biostimulation, photo-thermal effects, photoablation, plasma-induced ablation, photo-acoustic effects, photon transport Spectroscopy: Absorption, diffuse reflectance, fluorescence, Raman and tissue spectroscopy Bioimaging Principles and Techniques: Introduction to optical microscopy, principle of image formation, amplitude and phase microscopy, polarization, fluorescence and confocal microscopy, optical diffraction tomography and new microscopic techniques. 3D Bioimaging: Optical coherence tomography, polarimetry, diffuse optical tomography, photothermal imaging, photoacoustic imaging and optical biopsy. |
| Learning objectives | Students will learn the characteristics of light and lasers, laser-tissue interaction mechanisms, imaging conditions, and basics of 2D and 3D imaging modalities. With practical exercises, students will operate lasers and collect OCT images. |
| Bibliography | Recommended Reading: Prasad, P.N., “Introduction to Biophotonics”, (Wiley-VCH), 2003 Boudoux, C., "Fundamentals of Biomedical Optics, Niemz, H. M., "Laser-Tissue Interactions" Splinter, R., Hooper, B. A., "An introduction to Biomedical Optics" |
| Weblink | DBE |
| Admission requirements | Physics: electromagnetic theory and quantum mechanics basics, optics, electricity, and mechanics knowledge; Math: Fourier transform Limited student numbers (24), priority given to student in Biomedical Engineering |
| Course application | |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Friday | 10.15-12.00 | Hegenheimermattweg 167B, Lecture Hall 02. 097 |
Dates
| Modules |
Doctorate Biomedical Engineering: Recommendations (PhD subject: Biomedical Engineering) Modul: Biomedical Engineering Electives (Master's Studies: Biomedical Engineering) Module Specialisation: Medical Nanosciences (Master's Studies: Nanosciences) |
| Assessment format | record of achievement |
| Assessment details | Practical Work (mandatory) 45%, Quiz 10% and Final Exam 45% |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | one repetition, best attempt counts |
| Scale | 1-6 0,1 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Medicine |
| Offered by | Departement Biomedical Engineering (DBE) |