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28937-01 - Lecture: Early Safety Assessment and Alternatives to Animal Testing, 3Rs (1 CP)
| Semester | fall semester 2025 |
| Course frequency | Every fall sem. |
| Lecturers | Adrian Roth (adrian.roth@unibas.ch) |
| Content | Surrogate cell based models, predictive value, standpoint of industry and drug approval agencies Week 1: Early safety & 3Rs: from in silico to in vitro to in vivo (Prof. Dr. A. Roth) Week 2: 3R in Genetic Toxicology (Dr. Andreas Zeller) Week 3: Cell based models in drug safety (Prof. Dr. A. Roth / Dr. Stefan Kustermann) Week 4: Mathematics for Drug Hunting: From pharmacokinetic modeling to quantitative systems pharmacology (Dr. Benjamin Ribba) Week 5: In vitro Immunosafety assessment of novel medicines (Dr. F. Regenass) Week 6: Implementation of 3R principles in biomedical research (Prof. Dr. A. Roth; Student joint presentation) Week 7: Electronic written exam |
| Learning objectives | Alternatives to Animal Experiments in Toxicology |
| Bibliography | s. PubMed |
| Comments | Basic knowledge in Molecular Biology/ Genomics recommended. Film and sound recordings during the course are strictly forbidden (recorders may be confiscated) |
| Weblink | http://www.forschung3r.ch/de/news/index. |
| Admission requirements | Completed Bachelor degree |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Tuesday | 08.15-10.00 | Biozentrum, Seminarraum U1.191 |
| Comments |
the lecture on October, 7 is postponed to october 2, from 1:15 - 3:00 p.m. |
Dates
| Date | Time | Room |
|---|---|---|
| Tuesday 16.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.191 |
| Tuesday 23.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.191 |
| Tuesday 30.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 02.10.2025 | 13.15-15.00 | Biozentrum, Seminarraum U1.191 |
| Tuesday 14.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.191 |
| Tuesday 21.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.191 |
| Friday 31.10.2025 | 13.45-14.45 | Pharmazentrum, Hörsaal 1 |
| Modules |
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Pharmacy) Module: Translating Pharmacology and Drug Safety to Humans (Master's Studies: Drug Sciences) |
| Assessment format | continuous assessment |
| Assessment details | Electronic written exam (multiple choice) https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |