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44817-01 - Lecture: Concepts of Medicinal Chemistry (2 CP)
| Semester | fall semester 2025 |
| Course frequency | Every fall sem. |
| Lecturers |
Alexander Mayweg (alexander.mayweg@unibas.ch)
Thomas Ryckmans (thomas.ryckmans@unibas.ch) |
| Content | This course will cover principles and concepts of medicinal chemistry and its application to drug discovery. The course will commence with a historical background and introductory aspects to medicinal chemistry and subsequently cover the sciences impact on the various drug discovery phases and value chain (hit identification, lead identification, lead optimisation, clinical candidate selection) as well as future aspects of the science. |
| Learning objectives | The goal of the course is to gain a solid understanding of medicinal chemistry and how this research function is used across the drug discovery value chain in the identification and the design of new drugs. Key concepts and strategies of structure-activity and structure-property relationships, compound identification and optimisation and clinical candidate selection should be understood. Course students should obtain a broad overview of different drugs and drug classes from various examples and case studies contained in this course and should be able to recognise and recall key features of such drug molecules. |
| Bibliography | The following up-to-date textbook is recommended in support of the lecture course: The practice of Medicinal Chemistry, Camile George Wermuth, 4th Edition, AP Elsevier ISBN: 978-0-12-417205-0 |
| Comments | Lecturers: Alexander Mayweg and Thomas Ryckmans Film and sound recordings during the course are strictly forbidden (recorders may be confiscated) |
| Weblink | Department of Pharmaceutical Sciences |
| Admission requirements | Completed Bachelor degree |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Friday | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
Dates
| Date | Time | Room |
|---|---|---|
| Friday 19.09.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 26.09.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 03.10.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 10.10.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 17.10.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 24.10.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 31.10.2025 | 14.15-16.00 | no lecture, exam week |
| Friday 07.11.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 14.11.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 21.11.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 28.11.2025 | 14.15-16.00 | Dies Academicus |
| Friday 05.12.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 12.12.2025 | 14.15-16.00 | Pharmazentrum, Hörsaal 2 |
| Friday 19.12.2025 | 14.15-16.00 | no lecture, exam week |
| Wednesday 14.01.2026 | 09.00-10.30 | Pharmazentrum, Hörsaal 1 |
| Modules |
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Pharmacy) Module Specialisation: Medical Nanosciences (Master's Studies: Nanosciences) Module: Target Identification/Validation to Discovery of Modulators (Master's Studies: Drug Sciences) |
| Assessment format | continuous assessment |
| Assessment details | refer to this link: https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |