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15920-01 - Block course: Structural Biology and Biophysics (15 CP)
| Semester | fall semester 2025 |
| Course frequency | Every fall sem. |
| Lecturers |
Thomas Braun (thomas.braun@unibas.ch)
Mohamed Chami (mohamed.chami@unibas.ch) Benjamin Engel (ben.engel@unibas.ch) Sebastian Hiller (sebastian.hiller@unibas.ch) Roderick Lim (roderick.lim@unibas.ch, Assessor) Timm Maier (timm.maier@unibas.ch) Timothy Sharpe (timothy.sharpe@unibas.ch) |
| Content | This Block Course will enable students to glean deep insight into the nanoscopic world of biomolecules that drive functional cellular processes. Here, you will gain a fundamental understanding of the cutting-edge computational tools, experimental methods and quantitative analytical techniques being used to resolve biomolecular structures and their interactions correlated across atomic, molecular and cellular length scales. This course consists of three main themes: protein design, theoretical concepts and experimental research. First, students will be introduced to AI-based structural prediction and protein design. Second, you will participate in lectures to learn about the theoretical underpinnings of structural biology and biophysical methods. Third, all students will carry out weekly research projects using different combinations of methods and analyses. As a bonus, students will build and test their own designer proteins. Topics - computational tools including AI-based structure prediction - protein design, expression and purification - atomic force microscopy - cryo-electron microscopy and tomography - X-ray crystallography - nuclear magnetic resonance - surface plasmon resonance - isothermal calorimetry - mass photometry |
| Comments | For biology students only Limited number of places Compulsory attendance |
| Weblink | https://adam.unibas.ch |
| Admission requirements | Successful completion of the first two years of the BSc Biology with the module Molecular Biology in the second year. The grade of the module Molecular Biology must be sufficient (at least grade 4). Good knowledge of the main lecture Structural Biology (module Biologie 4). |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| Block | See individual dates | ||
| täglich | See individual dates | ||
| täglich | See individual dates | ||
| täglich | See individual dates | ||
| täglich | See individual dates | ||
| Comments |
Block course: 15.9.-24.10.2025, Monday to Friday, 8:00-18:00 A detailed schedule will be provided by the lecturers in due time. |
Dates
| Date | Time | Room |
|---|---|---|
| Monday 15.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Monday 22.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Monday 22.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Monday 22.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Tuesday 23.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Tuesday 23.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Tuesday 23.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Wednesday 24.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Wednesday 24.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Wednesday 24.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Thursday 25.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Thursday 25.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Thursday 25.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Friday 26.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Friday 26.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Friday 26.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Monday 29.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Monday 29.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Monday 29.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Tuesday 30.09.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Tuesday 30.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Tuesday 30.09.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Wednesday 01.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Wednesday 01.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Wednesday 01.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Thursday 02.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Thursday 02.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Thursday 02.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Friday 03.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Friday 03.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Friday 03.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Monday 06.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Monday 06.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Monday 06.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Tuesday 07.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Tuesday 07.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Tuesday 07.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Wednesday 08.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Wednesday 08.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Wednesday 08.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Thursday 09.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Thursday 09.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Thursday 09.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Friday 10.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Friday 10.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Friday 10.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Monday 13.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Monday 13.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Monday 13.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Tuesday 14.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Tuesday 14.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Tuesday 14.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Wednesday 15.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Wednesday 15.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Wednesday 15.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Thursday 16.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.197 |
| Thursday 16.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Thursday 16.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Friday 17.10.2025 | 08.15-10.00 | Biozentrum, Seminarraum U1.191 |
| Friday 17.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.090 |
| Friday 17.10.2025 | 10.00-17.00 | Biozentrum, Seminarraum 02.094 |
| Modules |
Majors: Molecular Biology and Integrative Biology (Bachelor's Studies: Biology (Start of studies before 01.08.2022)) Modul: Computational Biology (Bachelor's Studies: Computational Sciences) Module: Block Course (Master's degree subject: Biology) Module: Computational Biology (Bachelor's Studies: Computational Sciences (Start of studies before 01.08.2023)) Module: Specialization in Molecular Biology (Bachelor's Studies: Biology) |
| Assessment format | continuous assessment |
| Assessment details | Exam: 07.11.2025, 9-12 am, Biozentrum, lecture hall U1.131 |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Biozentrum |