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58301-01 - Lecture: Metals in Biology (3 CP)
| Semester | fall semester 2025 |
| Course frequency | Irregular |
| Lecturers | Thomas R. Ward (thomas.ward@unibas.ch, Assessor) |
| Content | Basics of protein structure Metal cofactors and their interactions with proteins Analysis of key metalloenzymes including: Hydrolases, Oxygenases, Oxidases, Hydrogenases, Nitrogenase, Redox-proteins, Oxygen evolving complex, Photosystem II, Metal trafficking in cells, Metal homeostasis, DNA-binding proteins, Biomimetic chemistry, Artificial Metalloenzymes etc. Metals in medicine Selected topics from current literature |
| Learning objectives | Identify key features of metalloenzymes and enzyme mimics Deduce and draw reasonable reaction mechanisms catalyzed by metalloenzymes Understand the role of metalloenzymes in solving energy-related grand challenges Design functional enzyme mimics Critically analyze the structure and function of metalloproteins |
| Bibliography | Principles of Bioinorganic Chemistry, 1994, Stephen J. Lippard, Jeremy M. Berg, University Science Books Biological Inorganic Chemistry: Structure and Reactivity, 2nd Ed. 2007, H. B. Gray et al., University Science Books Various up-to-date review articles |
| Comments | For the timely organization of the access to the Rosental campus, students of the University of Basel must register on services.unibas.ch until September 8th, 2025. Access to building BPR-1060 via gate 1047 only. |
| Course application | Register on services.unibas.ch For the timely organization of the access to the Rosental campus, students of the University of Basel must register on services.unibas.ch until September 8th, 2025. Access to building BPR-1060 via gate 1047 only. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Thursday | 13.15-16.00 | Campus Rosental 1060, Seminarraum 7.48 |
Dates
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module: Inorganic Chemistry (Master's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |