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55001-01 - Lecture: Biocatalysis for Organic Synthesis (3 CP)
| Semester | fall semester 2025 |
| Course frequency | Irregular |
| Lecturers | Valentin Köhler (valentin.koehler@unibas.ch, Assessor) |
| Content | The main objective is to discuss enzyme catalysis for fine chemical synthesis and includes the following chapters: general aspects of enzyme catalysis, hydrolytic reactions, reductions, oxidations, formation of C-C bonds, addition and elimination, transfer reactions, halogenation and dehalogenation. Mechanisms, stereochemistry, cascade catalysis, directed evolution, enzyme repurposing, process considerations, and other topics will also be addressed. |
| Learning objectives | The primary aim is to learn the central transformations frequently employed in biotransformations and apply this knowledge to synthesis planning for simple molecules. |
| Bibliography | The foundation of the lecture is the book ‘Biotransformations in Organic Chemistry, 7th edition’ by Kurt Faber, available on the University net. An additional resource is the book ‘Biocatalysis in Organic Synthesis’ by Nicholas J. Turner and Luke Humphreys. Research articles contribute to the lecture content. |
| Course application | Register on services.unibas.ch |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Monday | 13.15-15.00 | Chemie, Organische, Kleiner Hörsaal OC |
| wöchentlich | Tuesday | 09.15-10.00 | Campus Rosental 1060, Seminarraum 7.48 |
Dates
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module: Mixed Topics (Master's Studies: Chemistry) Module: Organic Synthesis (Bachelor's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment details | Presentation of a recent research article and written exam at the end of the course. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |