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46375-01 - Lecture: From Novel Targets to Novel Therapeutic Modalities (2 CP)
| Semester | spring semester 2026 |
| Course frequency | Every spring sem. |
| Lecturers |
Alex Odermatt (alex.odermatt@unibas.ch, Assessor)
Adrian Roth (adrian.roth@unibas.ch) |
| Content | 1. Introduction to the lecture series: From Novel Targets to Novel Therapeutic Modalities 2. Modern Drug Development starts with the Patient: Making use of "Real World Data" 3. Nucleic Acid based Therapeutics: from RNAi to Antisense Oligos 4. Development of Antisense Oligonucleotide Drugs 5. Small Molecule Drug Discovery: A Journey Through the Rule of 5 Space and Beyond 6. Mechanistic, Statistical and Causal Modelling in Drug Discovery 7. Gene and cell therapies 8. From Monoclonal Antibodies to engineeered Bi-Specifics 9. New Treatment Avenues: Personalized Healthcare and Understanding Individual Drivers of Response |
| Learning objectives | Know the basics on nucleic acid based therapeutics and understand the issues relevant for the development of antisense oligonucleotide drugs. Know the basics about monoclonal antibodies used as drugs. Understand issues relevant to classic and new small molecules as well as peptide drugs. Know the basics of gene and stem cell therapies. Know the basics of patenting of drug modalities. |
| Bibliography | Review Articles that will be distributed during the lectures |
| Comments | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated |
| Weblink | Department of Pharmaceutical Sciences |
| Admission requirements | Completed Bachelor degree |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Thursday | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
Dates
| Date | Time | Room |
|---|---|---|
| Thursday 19.02.2026 | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
| Thursday 26.02.2026 | 08.15-12.00 | Fasnachtsferien |
| Thursday 05.03.2026 | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
| Thursday 12.03.2026 | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
| Thursday 19.03.2026 | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
| Thursday 26.03.2026 | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
| Thursday 02.04.2026 | 08.15-12.00 | Ostern |
| Thursday 09.04.2026 | 08.15-12.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 21.04.2026 | 08.45-09.45 | Biozentrum, Hörsaal U1.101 |
| Modules |
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Pharmacy) Module Specialisation: Medical Nanosciences (Master's Studies: Nanosciences) Module: Target Identification/Validation to Discovery of Modulators (Master's Studies: Drug Sciences) |
| Assessment format | continuous assessment |
| Assessment details | Refert to the list at https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |