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19520-01 - Lecture: Dynamics and maintenance of the Genome: DNA Replication, Repair, Recombination (2 CP)
| Semester | spring semester 2026 |
| Course frequency | Every 2nd spring sem |
| Lecturers | Primo Leo Schär (primo.schaer@unibas.ch, Assessor) |
| Content | With many genomes having been sequenced, our understanding of the basic enzymology that ensures its replication and faithful transmission from mother to daughter cells now takes center stage. The lectures will cover mechanisms, regulation and biological significance of DNA metabolism in all forms. This will include general aspects of genome organization and dynamics, the enzymology, control and coordination of DNA replication, and the formation and repair of the various forms of DNA damage that occur continuously in our cells. In addition to the molecular and mechanistic aspects, the course will illustrate the significance of genome instability and maintenance in development, carcinogenesis, premature ageing and other forms of genetic degenerative conditions. |
| Bibliography | Research papers to be announced by speakers https://adam.unibas.ch |
| Weblink | Graduate Teaching Program |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Thursday | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
Dates
| Date | Time | Room |
|---|---|---|
| Thursday 19.02.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 26.02.2026 | 16.15-18.00 | Fasnachtsferien |
| Thursday 05.03.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 12.03.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 19.03.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 26.03.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 02.04.2026 | 16.15-18.00 | Ostern |
| Thursday 09.04.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 16.04.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.193 |
| Thursday 23.04.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 30.04.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 07.05.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 14.05.2026 | 16.15-18.00 | Auffahrt |
| Thursday 21.05.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Thursday 28.05.2026 | 16.15-18.00 | Biozentrum, Seminarraum U1.191 |
| Modules |
Cycle G: Gene Expression and Epigenetics (Master's Studies: Molecular Biology (Start of studies before 01.08.2025)) Doctorate Biochemistry: Recommendations (PhD subject: Biochemistry) Doctorate Biophysics: Recommendations (PhD subject: Biophysics) Doctorate Cell Biology: Recommendations (PhD subject: Cell Biology) Doctorate Computational Biology: Recommendations (PhD subject: Computational Biology) Doctorate Genetics: Recommendations (PhD subject: Genetics) Doctorate Microbiology: Recommendations (PhD subject: Microbiology) Doctorate Molecular Biology: Recommendations (PhD subject: Molecular Biology) Doctorate Neurobiology: Recommendations (PhD subject: Neurobiology) Doctorate Pharmacology: Recommendations (PhD subject: Pharmacology) Doctorate Structural Biology: Recommendations (PhD subject: Structural Biology) Module Specialisation: Molecular Biology (Master's Studies: Nanosciences) Module: Cycle G: Gene Expression and Epigenetics (Master's Studies: Molecular Biology) Vertiefungsfächer Theorie und Vertiefungsfächer Biologie (Master's Studies: Computational Biology and Bioinformatics) |
| Assessment format | continuous assessment |
| Assessment details | Participation Short presentations of research papers by students |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Biozentrum |