Back to selection
| Semester | spring semester 2026 |
| Further events belonging to these CP |
77673-01 (Master's project) 77673-02 (Master's project) 77673-03 (Master's project) 77673-04 (Master's project) 77673-05 (Master's project) 77673-06 (Master's project) 77673-07 (Master's project) |
| Course frequency | Once only |
| Lecturers |
Ute Gschwandtner (ute.gschwandtner@unibas.ch)
Roselind Lieb (roselind.lieb@unibas.ch, Assessor) |
| Content | Masterprojekt: "Diagnose und frühzeitige Risikoeinschätzung von Parkinson-Demenz" (Ute Gschwandtner) Neurodegenerative disorders begin insidiously in midlife and are relentlessly progressive. Currently, there exists no established curative or protective treatment, and they constitute a major and increasing health problem and, in consequence, an economic burden in aging populations globally. Parkinson’s disease (PD), following Alzheimer’s disease (AD), is the second most common neurodegenerative disorder worldwide, estimated to occur in approximately 1% of population above 60 and at least in 3% in individuals above 80 years of age. In Switzerland, about 15’000 persons are diagnosed with PD. In addition to motor signs, which due to recent medical progress can be treated satisfactorily in most cases, non-motor symptoms and signs severely affect the well-being of patients. They include mood disorders, psychosis, cognitive decline, disorders of circadian rhythms, as well as vegetative and cardiovascular dysregulation. Neurodegeneration in PD progresses for years before clinical diagnosis is possible, at which time e.g. 80% of dopaminergic neurons in the Substantia nigra are lost already. Therefore, any clinical targeting disease modification, prognosis and personalized treatment including guiding the indication for deep brain stimulation (DBS) requires reliable and valid biomarkers. The main goal of this research project is the identification of a pertinent set of genetic and neurophysiological markers for diagnosis and early risk assessment of PD-dementia. Our approach has a distinct interdisciplinary basis, in that it fosters close collaborations between physicians, neuroscientists, psychiatrists, psychologists, computer scientists and statisticians. |
| Learning objectives | Methodische Erlenung von Risikomarker (neuropsychiatrisch, elektrophysiologisch, neuropsychologisch, etc.) bei Patienten mit Parkinson Krankheit |
| Bibliography | Aarsland, D. et al. Cognitive impairment in incident, untreated Parkinson disease: The Norwegian ParkWest Study. Neurology 72, 1121-1126 (2009) Riedel, O. et al. Frequency of dementia, depression, and other neuropsychiatric symptoms in 1,449 outpatients with Parkinson’s disease. Journal of neurology 257, 1073-1082 (2010) Litvan, I. et al. Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Dis-order Society Task Force guidelines. Movement Disorders 27, 349-356 (2012) |
| Comments | Bei Patienten mit Parkinson-Krankheit sollen verschiedene Demenz-Risikofaktoren systematisch analysiert werden. Ein diagnostischer Interviewkontakt mit den Patienten ist möglich. Die individuellen Termine werden mit der Betreuungsperson persönlich vereinbart. Zugehöriges Kolloquium (StO24): "Masterarbeiten in der Klinischen Psychologie und Epidemiologie". |
| Admission requirements | Abgeschlossenes Bachelorstudium Psychologie. Schreiben einer MSc-Arbeit im Bereich Klinische Psychologie und Epidemiologie. |
| Language of instruction | German |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Module: Master's Project in Health and Interventions (Master's Studies: Psychology) |
| Assessment format | continuous assessment |
| Assessment details | Für die regelmässige Teilnahme am Masterprojekt (StO24) werden 5 KP vergeben, zusätzlich werden mit dem Masterkolloquium (StO24) 2 KP erworben (StO24). Insgesamt müssen im Modul "Masterprojekt" (StO24) 14 KP erworben werden. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | no repetition |
| Responsible faculty | Faculty of Psychology, studiendekanat-psychologie@unibas.ch |
| Offered by | Faculty of Psychology |