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13182-01 - Lecture: C2: Functional Organization of the Cell Nucleus (2 CP)
| Semester | fall semester 2010 |
| Course frequency | Every 3rd fall sem. |
| Lecturers |
Ueli Aebi (ueli.aebi@unibas.ch)
Susan Gasser (susan.gasser@unibas.ch) Erich Nigg (erich.nigg@unibas.ch) Cora-Ann Schoenenberger (cora-ann.schoenenberger@unibas.ch, Assessor) |
| Content | In eukaryotic cells, the nucleus represents the most complex organelle. Nuclear architecture contributes to complex processes such as gene expression, DNA replication, transcription, recombination and repair, RNA processing, nucleocytoplasmic transport, and apoptosis. The lecture will focus on: chromosome organization and dynamics; DNA replication and transcription; nuclear organelles such as nuclear bodies and the nucleolus; RNA processing and the survival of motor neurons (SMN) gene complex; nuclear pore complexes and nucleocytoplasmic transport; the role of the small GTPase Ran in nucleocytoplasmic transport, spindle assembly and nuclear envelope breakdown; the nuclear lamina, lamin‐binding proteins, and nuclear envelope structure, assembly/ disassembly and dynamics; diseases related to nuclear defects; and the role of the nucleus in apoptosis. |
| Comments | Unter Mitwirkung von: Vincent Dion, Helder Ferreira, Peter Meister, (alle FMI), Anna Santamaria (Biozentrum) |
| Weblink | http://www.biozentrum.unibas.ch/graduate |
| Language of instruction | English |
| Use of digital media | Online, optional |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Cycle C: Growth & Development (PhD subject: Biochemistry) Cycle C: Growth & Development (PhD subject: Biophysics) Cycle C: Growth & Development (PhD subject: Genetics) Cycle C: Growth & Development (PhD subject: Microbiology) Cycle C: Growth & Development (PhD subject: Cell Biology) Cycle C: Growth & Development (PhD subject: Pharmacology) Cycle C: Growth & Development (PhD subject: Neurobiology) Cycle C: Growth & Development (PhD subject: Bioinformatics) Cycle C: Growth & Development (PhD subject: Structural Biology) Cycle C: Growth & Development (Master Molecular Biology) Module Specialisation: Molecular Biology (Master Nanosciences) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg.: course registration; dereg.: teaching staff |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Biozentrum |