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50310-01 - Lecture with practical courses: Analytical Applications in Drug Discovery 1 CP

Semester spring semester 2020
Course frequency Every spring sem.
Lecturers Stephan Müller (stephan.mueller@unibas.ch, Assessor)
Content Examples for typical topics:
Introduction and toolbox: What to find where. Suppliers, literature, information, software
Advanced HPLC methods: UPLC, column materials, column switching
Application quantitative Bioanalysis; HPLC-UV
Method validation example
Advanced mass spectrometry: accurate mass and elemental composition; application in qualitative analysis
Advanced MS/MS experiments, data dependent analysis, ion mobility; application in chemical, biochemical and -omics analysis
noncovalent interaction analysis; application in binding assays
Application Biomarker Analysis; LC/MS-MS*
Application compound purity assessment workflow*

*if permission is granted and time sufficient
Learning objectives Insight and beginner's experience of analytical practise in research: You know material and information sources and providers, you can search, manage and extract literature on practical examples and derive a proposal for method development. You can use Excel for the evaluation of typical amounts of data and have to do some troubleshooting. You learn some more on advanced instrumental analytics, especially mass spectrometry.
Bibliography Literature: Will mostly have to be looked up..
Comments THE course for you digital natives :-)

Film and sound recordings during the course are strictly forbidden (recorders may be confiscated)
Weblink Participants webpage, please register

 

Admission requirements Completed Bachelor degree
Beside the usual booking over MonA registration under unibas.smv3.ch is needed!

Laptop with power supply for 2h during the lessons
Recent MS Office software or equivalent
Standard web browser (Safari, Firefox, Chrome, MSE)
Structure Editor: Download and install ChemAxon's Marvin suite for structure design.
Scientific calculator
Course application 1. University booking (Belegen) as usual over MoNa
2. Register at unibas.smv3.ch to access the software and material download
Language of instruction English
Use of digital media Online course
Course auditors welcome

 

Interval weekly
Date 25.02.2020 – 07.04.2020
Time Tuesday, 15.15-17.00 Zz- inaktiv Biozentrum Altbau, Seminarraum 104
Date Time Room
Tuesday 25.02.2020 15.15-17.00 Zz- inaktiv Biozentrum Altbau, Seminarraum 104
Tuesday 03.03.2020 15.15-17.00 Fasnachtsferien
Tuesday 10.03.2020 15.15-17.00 Zz- inaktiv Biozentrum Altbau, Seminarraum 104
Tuesday 17.03.2020 15.15-17.00 Zz- inaktiv Biozentrum Altbau, Findet online statt
Tuesday 24.03.2020 15.15-17.00 Zz- inaktiv Biozentrum Altbau, Findet online statt
Tuesday 31.03.2020 15.15-17.00 Zz- inaktiv Biozentrum Altbau, Findet online statt
Tuesday 07.04.2020 15.15-17.00 Zz- inaktiv Biozentrum Altbau, Findet online statt
Modules Electives Master Drug Sciences: Recommendations (Master's Studies: Drug Sciences)
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy)
Assessment format continuous assessment
Assessment details The examination will take place in form of exercises or online or paper quizzes during the lessons. The tasks will require informatics tools and internet access. Therefore, registration at unibas.smv3.ch and a PC/Mac with web access and MS Office during the lessons is mandatory.
Assessment registration/deregistration Reg./dereg.: course registr./cancel registr. via MOnA
Repeat examination no repeat examination
Scale Pass / Fail
Repeated registration as often as necessary
Responsible faculty Faculty of Science, studiendekanat-philnat@unibas.ch
Offered by Departement Pharmazeutische Wissenschaften

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