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| Semester | fall semester 2015 |
| Course frequency | Irregular |
| Lecturers | Thomas R. Ward (thomas.ward@unibas.ch, Assessor) |
| Content | Basics of protein structure Metal cofactors and their interactio with proteins Metals in medicine Analysis of key metalloenzymes including Hydrolases, Oxygenases, Oxidases, Hydrogenases, Transport proteins, DNA-binding proteins etc. Energy-related challenges: The solution is bio-inorganic Selected topics from current literature |
| Learning objectives | Identify key features of metalloenzymes and enzyme mimics. Deduce and draw reasonable reaction mechanisms of metalloenzymes. Understand the role of metalloenzyme in solving energy-related grand challenges. Propose realistic enzyme mimics |
| Bibliography | Principles of Bioinorganic Chemistry, 1994, Stephen J. Lippard, Jeremy M. Berg, University Science Books Biological Inorganic Chemistry: Structure and Reactivity, 2nd Ed. 2007, H. B. Gray et al., University Science Books Various up-to-date review articles from Chem. Rev., Chem. Soc. Rev., Angew. Chem. and Acc. Chem. Res. |
| Weblink | structure of metalloenzymes made easy |
| Admission requirements | Bachelor in chemistry with a solid background in organometallic and coordination chemistry Basic knowledge in biochemistry is an asset |
| Course application | Belegen via MOnA. |
| Language of instruction | English |
| Use of digital media | Online, optional |
| Interval | Weekday | Time | Room |
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No dates available. Please contact the lecturer.
| Modules |
Doktorat Chemie: Empfehlungen (PhD subject: Chemistry) Module Specialisation (Master Chemistry) Module Specialisation: Chemistry (Master Nanosciences) |
| Assessment format | continuous assessment |
| Assessment details | One hour written examination |
| Assessment registration/deregistration | Reg.: course registration; dereg.: teaching staff |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |