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| Semester | spring semester 2017 |
| Course frequency | Every spring sem. |
| Lecturers |
Stefan Borgwardt (s.borgwardt@unibas.ch)
Anne Eckert (anne.eckert@unibas.ch) Matthias Emanuel Liechti (matthias.liechti@unibas.ch, Assessor) Nicole Schaeren-Wiemers (nicole.schaeren-wiemers@unibas.ch) |
| Content | Order may change Week 1: Introduction (M. Liechti), Nervous Tissue Par 1 (N. Schären-Wiemers) Week 2: Nervous Tissue Part 2 and Mechanisms of Neurodegeneration (N. Schären-Wiemers) Week 3: Mechanisms of Neurodegeneration Part 2 and Axonal Transport (N. Schären-Wiemers) Week 4: Cellular Assays (A. Eckert) and Cholinergic system (M. Liechti) Week 5: Monoamine, GABA and glutamargic systems (M. Liechti) Week 6: Neurological evaluation (M. Hardmeier); Neuroimaging (St. Borgwardt) Week 7: MC-Exam |
| Learning objectives | To understand the structural and function basics of the nervous system and how chemicals and drugs interact with neuronal structures and functions. Ability to evaluate example cases. |
| Bibliography | Lecture slides on ADAM. Klaassen, Casaretts & Dull’s, Toxicology, The basis science of poisons, Chapter: Toxic responses of the nervous system. Goodman & Gilman’s, Manual of Pharmacology and Therapeutics, paperback, McGraw Hill Medical, (available as small paper back or full hard cover book) a. Chapter 6-11: Drugs acting at synaptic and neuroeffector junctional sites b. Chapter 12-23: Drugs acting on the central nervous system and neurotransmission in the CNS Reading assignments (ADAM) Acute Toxicities of Organophosphates and Carbamates, Chapter 1 by JE Chambers and RL Carr; Handbook of Neurotoxicology Vol I by EJ Massaro, Humana Press, 2010 AND Neurotoxic effects of substitute amphetamines in rodents; Chapter 11 by JP O’Callaghan and DB Miller and Dopamine and Neuronal Damage. Handbook of Neurotoxicology Vol I by EJ Massaro, Humana Press, 2010 |
| Comments | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated |
| Admission requirements | Completed Bachelor in Pharmaceutical Sciences |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Electives Master Science in Pharmacy: Recommendations (Master Science in Pharmacy (Start of studies before 01.08.2016)) Electives Master Science in Pharmacy: Recommendations (Master Science in Pharmacy) Module Specialisation: Toxicology (Master Pharmaceutical Sciences (Start of studies before 01.08.2016)) Module Specific Knowledge in Toxicology (Master Toxicology (Start of studies before 01.08.2016)) (Pflicht) Module Translating Pharmacology and Drug Safety to Humans (Master Drug Sciences) |
| Assessment format | continuous assessment |
| Assessment details | Please refert to the list: http://pharma.unibas.ch/teaching/leistungsueberpruefungen/lluep/ |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |