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| Semester | fall semester 2022 |
| Course frequency | Every fall sem. |
| Lecturers |
Hans Deyhle (hans.deyhle@unibas.ch)
Srinivas Madduri (srinivas.madduri@unibas.ch) Bert Müller (bert.mueller@unibas.ch, Assessor) Bekim Osmani (bekim.osmani@unibas.ch) Griffin Rodgers (griffin.rodgers@unibas.ch) Guido Sigron (guido.sigron@unibas.ch) |
| Content | The students will understand the atomic and molecular structure of solid states and soft materials. Based on this knowledge, the students will be able to draw conclusions about material properties on the macroscopic scale to select and tailor their characteristics for medical applications including the broad variety of medical implants made from metals, ceramics, polymers, composites, etc. The characterization of materials down to the atomic level will be discussed, as this is the main prerequisite for innovations and improvements. This lecture series also covers selected fabrication procedures for a variety of implants, including a discussion of phase transitions and thermally activated processes. Finally, the biocompatibility of implant materials will be explored. Biocompatibility does not only depend on the chemical composition but also on the surface morphology and the specific host tissue. • Introduction into biomaterials science • Nanoscience for human health • Challenges to be solved by biomedical engineers • Concepts in materials science for medical implants • Crystalline structure of condensed matter • Binding in condensed matter • Polymeric solid states • Materials in regenerative medicine • Standards of biocompatibility tests • Sterilization methods • Polymers for medical implants including hydrogels • Crystal defects • Preparation of surfaces and the skin of crystals • Formation of solid-state materials • Metal-based implants and scaffolds • Natural and synthetic ceramics for implants and regenerative medicine • Characterization of materials • Combining materials for computer-brain interface • Computed tomography for clinical use and research • Materials and technologies in oral health • Current research in dentistry • Stimuli-responsive liposomes • X-ray scattering for materials characterization • Materials selection in implant design • Employing materials science for improving human health: Example incontinence treatment |
| Learning objectives | The students can explain: • fabrication and shaping of biomaterials for medical implants • uses and selection criteria for biomaterials • how to exploit the structure-function relationship of materials • tailoring biomaterials with respect to corrosion behavior and biocompatibility. |
| Bibliography | Ratner, Hoffmann, Schoen, Lemons: "Biomaterials Science: An Introduction to Materials in Medicine", 2nd edition, Elsevier Academic Press. |
| Weblink | DBE |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Wednesday | 08.15-12.00 | Zz-Gewerbestrasse 14, Vorlesungsraum DBE 14.03.002 |
| Modules |
Module Specialisation: Medical Nanosciences (Master's Studies: Nanosciences) Module: Biomedical Engineering (Master's Studies: Biomedical Engineering) |
| Assessment format | record of achievement |
| Assessment details | individual oral examination, 30 min: 19.01.2023 or 23.01.2023, exact times will be communicated by email in December |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | one repetition, best attempt counts |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Medicine |
| Offered by | Departement Biomedical Engineering (DBE) |