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| Semester | fall semester 2023 |
| Course frequency | Irregular |
| Lecturers | Thomas R. Ward (thomas.ward@unibas.ch, Assessor) |
| Content | Basics of protein structure Metal cofactors and their interactions with proteins Analysis of key metalloenzymes including: Hydrolases, Oxygenases, Oxidases, Hydrogenases, Nitrogenase, Redox-proteins, Oxygen evolving complex, Photosystem II, Metal trafficking in cells, Metal homeostasis, DNA-binding proteins, Biomimetic chemistry, Artificial Metalloenzymes etc. Metals in medicine Selected topics from current literature |
| Learning objectives | Identify key features of metalloenzymes and enzyme mimics Deduce and draw reasonable reaction mechanisms catalyzed by metalloenzymes Understand the role of metalloenzymes in solving energy-related grand challenges Design functional enzyme mimics Critically analyze the structure and function of metalloproteins |
| Bibliography | Principles of Bioinorganic Chemistry, 1994, Stephen J. Lippard, Jeremy M. Berg, University Science Books Biological Inorganic Chemistry: Structure and Reactivity, 2nd Ed. 2007, H. B. Gray et al., University Science Books Various up-to-date review articles |
| Comments | Access to Rosental 1060, room 7.48 only via gate BPR 1047, Mattenstrasse 24a. Students of the University of Basel have to register on services.unibas.ch for an access to the Rosental until September 11th, 2023. |
| Course application | Register on services.unibas.ch Registration until September 11th, 2023 for access to the Rosental. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Thursday | 13.15-16.00 | Campus Rosental 1060, Seminarraum 7.48 |
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module: Inorganic Chemistry (Master's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |