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44812-01 - Lecture: Mechanisms of Toxicity 1 CP

Semester fall semester 2018
Course frequency Every fall sem.
Lecturers Stephan Krähenbühl (stephan.kraehenbuehl@unibas.ch, Assessor)
Content The following mechanisms will be discussed: general principles of interaction with cells and proteins, repair mechanisms, mitochondrial respiratory chain, uncoupling, mitochondrial DNA, mitochondrial fatty acid oxidation. ER stress response, redox reactions, Lysosomes, phospholipidosis, cytokines, inflammasome, apoptosis, necrosis, nuclear receptors, ion homeostasis
Learning objectives Students should know the principle toxicological mechanisms how toxicants can damage cell organelles and cells.
Bibliography Klaassen CD, Casarett and Doull's Essentials of Toxicology. McGraw-Hill. Newest edition.
Klaassen CD. Casarett and Doull's Toxicology, the basic Science of Poisons. McGraw-Hill. Newest edition.
Comments Film and sound recordings during the course are strictly forbidden (recorders may be confiscated)

 

Language of instruction English
Use of digital media No specific media used

 

Interval Weekday Time Room

No dates available. Please contact the lecturer.

Modules Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy)
Module: Translating Pharmacology and Drug Safety to Humans (Master's Studies: Drug Sciences)
Assessment format continuous assessment
Assessment details refer to this link: https://pharma.unibas.ch/de/teaching/pruefungen-exams/performance-assessments/course-accompanying-examinations/
Assessment registration/deregistration Reg.: course registration, dereg: cancel course registration
Repeat examination no repeat examination
Scale 1-6 0,5
Repeated registration as often as necessary
Responsible faculty Faculty of Science, studiendekanat-philnat@unibas.ch
Offered by Departement Pharmazeutische Wissenschaften

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