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| Semester | fall semester 2018 |
| Course frequency | Every fall sem. |
| Lecturers |
Hermann Gram (hermann.gram@unibas.ch)
Steffen Hartmann (steffen.hartmann@unibas.ch) Thomas Huber (thomas.huber@unibas.ch) Frank Kolbinger (frank.kolbinger@unibas.ch) Roland Preston (roland.preston@unibas.ch) Daniel Ricklin (d.ricklin@unibas.ch, Assessor) Maximilian Woisetschläger (maximilian.woisetschlaeger@unibas.ch) |
| Content | Therapeutic antibodies have evolved into a highly important and rapidly growing sector of modern drug therapy, with several antibody-based drugs being available to the clinic and many more in clinical development. In this lecture series, experts from pharmaceutical industry with broad experience in antibody development will guide through the various aspects of bringing a therapeutic antibody from discovery to the clinic. In particular, the lectures will cover the following topics: - Structure and characteristics of immunoglobulins, and generation of monoclonal antibodies - Effector functions and pharmacokinetic properties of antibodies - Preclinical development, characterization and production of therapeutic antibodies - Clinical development and therapeutic use of antibody-based therapeutics - Examples and case studies of therapeutic antibodies in the clinic - Emerging trends in the discovery and development of antibody-based drugs As part of the lecture series, we will also organize a guided tour at one of Novartis’ antibody facilities (see special announcement). |
| Learning objectives | During this lecture series, the students will learn about: - the key structural, functional and pharmaceutical features of antibodies - established and emerging strategies to design antibody-based drugs - options to produce antibodies at the laboratory or industrial scale - considerations and examples of using therapeutic antibodies in the clinic |
| Comments | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated) |
| Weblink | ADAM |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy) Module: Target Identification/Validation to Discovery of Modulators (Master's Studies: Drug Sciences) |
| Assessment format | continuous assessment |
| Assessment details | Electronic written examination at the end of the semester (60 min, iPad) https://pharma.unibas.ch/de/teaching/pruefungen-exams/performance-assessments/course-accompanying-examinations/ |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |