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| Semester | spring semester 2019 |
| Course frequency | Every spring sem. |
| Lecturers | Stephan Müller (stephan.mueller@unibas.ch, Assessor) |
| Content | In contrast to the Bachelor lecture this one is much more interactive. We will work on practical examples using modern online informatics sources on some of the following topics: Introduction and toolbox: What to find where. Suppliers, literature, information, software Advanced HPLC methods: UPLC, column materials, column switching Application quantitative Bioanalysis; HPLC-UV Method validation example Advanced mass spectrometry: accurate mass and elemental composition; application in qualitative analysis Advanced MS/MS experiments, data dependent analysis, MSe ion mobility; application in chemical, biochemical and -omics analysis noncovalent interaction analysis; application in binding assays Application Biomarker Analysis; LC/MS-MS* Application compound purity assessment workflow; LC/MS and NMR* *if permission is granted and time sufficient |
| Learning objectives | Insight and beginner's experience of analytical practise in research: You know material and information sources and providers, you can search, manage and extract literature on practical examples and derive a proposal for method development. You can use Excel for the evaluation of typical amounts of data and have to do some troubleshooting. You learn some more on advanced instrumental analytics, especially mass spectrometry. |
| Bibliography | Literature: Will mostly have to be looked up.. Tools: Download page of unibas.smv3.ch: https://unibas.smv3.ch/en/analytics-in-drug-discovery-msc/downloads-msc/ |
| Comments | THE course for you digital natives :-) Film and sound recordings during the course are strictly forbidden (recorders may be confiscated) |
| Weblink | Participants webpage, please register |
| Admission requirements | Beside the usual booking over MonA registration under unibas.smv3.ch is needed! Laptop with power supply for 2h during the lessons Recent MS Office software or equivalent Standard web browser (Safari, Firefox, Chrome, MSE) Structure Editor: Download and install ChemAxon's Marvin suite for structure design. MacOS and windows versions and the license file are available on the downloads page. We have a teaching license which is free for educational use Scientific calculator |
| Course application | 1. University booking (Belegen) as usual over MoNa 2. Registration at https://unibas.smv3.ch/en/registration for material and exams |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Course auditors welcome |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Electives Master Drug Sciences: Recommendations (Master's Studies: Drug Sciences) Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy) |
| Assessment format | continuous assessment |
| Assessment details | The examination will take place in form of exercises or online or paper quizzes during the lessons, and the tasks will require informatics tools and internet access. Therefore, registration at unibas.smv3.ch and a PC/Mac with web access and MS Office during the lessons is mandatory. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |