Back
| Semester | fall semester 2019 |
| Course frequency | Irregular |
| Lecturers |
Isabel Kolinko (isabel.kolinko@unibas.ch)
Michael Nash (michael.nash@unibas.ch, Assessor) |
| Content | Introduction to biomacromolecules; Measurement techniques for characterisation of biomacromolecules; Fundamentals of molecular recognition; Recombinant DNA; Protein engineering; Directed evolution; Protein folding; Polymers; Elastin-like polypeptides; Intelligent materials; Spatially localized hydrogels; Mechanical properties of proteins and macromolecules; Single-molecule force spectroscopy. |
| Learning objectives | The objective is to familiarise the students with a broad range of topics related to biotechnology, nanotechnology, and biophysics with a focus on current research and reading of scientific literature. |
| Bibliography | (1) Alberts, Molecular Biology (Ch.2 Cellular chemistry). (2) Ratner, Biomaterials Science (Ch. 2.3, 2.4 Polymers & hydrogels). (3) Walsh, Protein Biochemistry, (Ch. 2, Protein Structure). (4) Nath et. al. Analytical chemistry, 74(3): 504-509, 2002. (5) DeMonte, D., et. al. Proteins DOI: 10.1002/prot.24320, 2013. (6) Feldhaus, M.J., et al. Nature Biotechnology 21 (2): 163–70, 2003. (7) Link, A.J., et al. PNAS 103 (27): 10180–85, 2006. (8) Chen, I. et al. PNAS 108 (28): 11399–404, 2011. (9) Marín-Navarro, J., et. al. PloS One 10 (12). journals.plos.org: e0144289, 2015. (10) Christensen, T. et al. Biomacromolecules 14 (5): 1514–19, 2013. (11) Shimoboji, T., et al. PNAS. 99(26): 16592-16596, 2002. (12) Puchner, E.M. et al. PNAS. 105(36): 13385–13390, 2008. (13) Dietz, H., et al. PNAS 103 (5): 1244–47, 2006. |
| Comments | Access to 1078 only via gate 1047. Students of the University of Basel register via MOnA for an access to the Rosental please until September15th, 2019. ETH-students need to apply for a badge in advance with an email to: student-admin@bsse.ethz.ch prior the start of the lecture. |
| Course application | Belegen via MOnA. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module Specialisation: Molecular Biology (Master's Studies: Nanosciences) Module: Physical Chemistry (Master's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment details | Written critiques of reading assignments; In-class presentation; Final report (grant proposal format). |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |