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| Semester | spring semester 2020 |
| Course frequency | Every spring sem. |
| Lecturers | Matthias Hamburger (matthias.hamburger@unibas.ch, Assessor) |
| Content | The seminar will address the evaluation of physico-chemical, pharmacological/toxicological and biopharmaceutical properties of drugs, with a series of case studies. Case studies are on industrial discovery and development projects where the novel drug substance is in clinical development. Students will work in teams of 2 on a specific case. The individual projects, and specific questions to be addressed by the teams will be briefly presented by the lecturer at the start of the seminar. Students then select their individual projects. As a starting point groups will receive selected literature for their case study, and a catalogue of key questions to be addressed. The teams will address these questions, and discuss the specific case within the wider context, eg. possible industrial competitor projects addressing the same drug target. |
| Learning objectives | Participants know and understand the parameters which are important for the pharmaceutical and pharmacological/toxicological profiling of a compound. They are able to evaluate the suitability of a molecule as drug substance.They are able to evaluate the outcomes of a specific drug development program against the background of current knowledge. Students are able to summarize their findings in a concise written and oral form. |
| Bibliography | Key literature on each case study, and a catalogue of questions to be addressed, will be prepared and handed out by the lecturer. As general reference, the following book can be consulted: Molecular Drug Properties. Measurement and Prediction. R. Mannhold, H. Kubinyi, G. Folkers, Wiley-VCH 2007 |
| Comments | The seminar will be in English. The written report and oral presentation will be in English. Film and sound recordings during the course are strictly forbidden (recorders may be confiscated). |
| Admission requirements | Admission to the MSc in Drug Sciences Number of participants limited to 12. Attention: Students who want to attend have to send an email to manuela.rogalski@unibas.ch until 10 February 2020 at latest. You will be immediately informed whether you can attend or whether seminar is full, based on a First-come-First-Served basis. Only after receiving the email confirmation by Manuela Rogalski you can register for the seminar in MONA! |
| Course application | Attention: Students who want to attend have to send an email to manuela.rogalski@unibas.ch until 10 February 2020 at latest. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
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No dates available. Please contact the lecturer.
| Modules |
Electives Master Drug Sciences: Recommendations (Master's Studies: Drug Sciences) Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy) |
| Assessment format | continuous assessment |
| Assessment details | An oral presentation and a written report of the case study. pass/fail |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |