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| Semester | spring semester 2020 |
| Course frequency | Every spring sem. |
| Lecturers | Mihaela Zavolan (mihaela.zavolan@unibas.ch, Assessor) |
| Content | This course will introduce students to fundamental problems in Bioinformatics/Computational Biology such as: - Evolution: Mathematical models for the evolution of DNA sequences. - Alignment and Phylogeny reconstruction: inferring evolutionary relationships between sequences. - Functional annotation: Finding genes and regulatory sequences in fully sequenced genomes. - Families of coding sequences: Hidden Markov models of protein domains - Gene expression networks: Inferring regulatory factors driving gene expression. Students should have a good understanding of calculus, linear algebra, combinatorics and algorithms and should be familiar with concepts of molecular biology. |
| Learning objectives | Students learn about the basic problem domain of bioinformatics as well as a wide range of algorithms for sequence analysis. They will learn about the commonly used languages of bioinformatics (mostly Python) and will implement basic bioinformatics algorithms. |
| Weblink | https://adam.unibas.ch |
| Admission requirements | First year courses must be accomplished. Mathematical background is needed in calculus, linear algrebra, diffential equations. Knowledge about discrete mathematics, stochastic processes and fundamental computer science algorithms is a plus. Basic programming skills and basic understanding in physics, chemistry and molecular biology (cells, DNA, RNA, proteins, etc.) is necessary. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Cycle E: Computational and Systems Biology (Master's Studies: Molecular Biology) Module: Applications and Related Topics (Bachelor's Studies: Computer Science) Module: Computational Biology (Bachelor's Studies: Computational Sciences (Start of studies before 01.08.2018)) (Pflicht) Module: Computational Biology (Bachelor's Studies: Computational Sciences) Module: Computational Chemistry (Bachelor's Studies: Computational Sciences (Start of studies before 01.08.2018)) Module: Computational Physics (Bachelor's Studies: Computational Sciences (Start of studies before 01.08.2018)) Module: Computational Sciences II (Bachelor's Studies: Computational Sciences) Module: Computational Sciences II (Bachelor's Studies: Computational Sciences (Start of studies before 01.08.2018)) |
| Assessment format | continuous assessment |
| Assessment details | Written exam and exercises Exam: Thursday, May 28, 13-15h. Klingelbergstr. 61, Lounge (1301), Level E 13 (top floor) |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Biozentrum |