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| Semester | spring semester 2021 |
| Course frequency | Irregular |
| Lecturers |
Samuel Lorenz Bader (samuellorenz.bader@unibas.ch)
Christian Bauer (christian.bauer@unibas.ch) Balázs Bobály (balazs.bobaly@unibas.ch) Gisela Helene Fontaine (giselahelene.fontaine@unibas.ch) Rolf Hilfiker (rolf.hilfiker@unibas.ch) Steffen Kiessig (steffen.kiessig@unibas.ch) Marius Koch (ma.koch@unibas.ch) Claudia Michael (claudia.michael@unibas.ch) Bernd Moritz (bernd.moritz@unibas.ch) Maria Anna Schwarz (maria.schwarz@unibas.ch, Assessor) |
| Content | Basics of solid forms (salts, co-crystals, polymorphs) • Impact on bioavailability • Screening • Properties • Thermodynamics Selected methods to characterize solids (XRPD, DSC, TG, Raman) Introduction and overview of analytical techniques used in pharmaceutical industry; differentiation between molecule categories, Q-standards, development process, validation Inorganic trace element analysis AAS (flame, graphite furnace, cold vapour, hydride generation), ICP-OES, ICP-MS, Sample preparation, Applications in pharmaceutical analysis Mass spectrometry 1 (Instrumentation, Spectra, Small molecule applications) Mass spectrometry 2 (Peptide mapping and applications) Mass spectrometry 3 (Protein molecular weight measurement and applications) CE basics and applications of proteins (GCE, cIEF, CZE) LC techniques applied for small and large molecules CE applications of BioPharm (deamidation, pegylation, ACE, chiral,….) Spectroscopic methods Posttranslational modifications of proteins (general overview) Deeper insight into the analysis of glycans (CE, HPLC, MS) |
| Course application | https://services.unibas.ch |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Thursday | 14.30-17.15 | - Online Präsenz - |
| Date | Time | Room |
|---|---|---|
| Thursday 04.03.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 11.03.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 18.03.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 25.03.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 01.04.2021 | 14.30-17.15 | Ostern |
| Thursday 08.04.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 15.04.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 22.04.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 29.04.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 06.05.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 13.05.2021 | 14.30-17.15 | Auffahrt |
| Thursday 20.05.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 27.05.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Thursday 03.06.2021 | 14.30-17.15 | - Online Präsenz -, -- |
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module: Mixed Topics (Master's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |