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13186-01 - Lecture: Frontiers in RNA Biology 2 CP

Semester fall semester 2021
Course frequency Every 2nd fall sem.
Lecturers Marc B├╝hler (, Assessor)
Helge Grosshans (
Content The discovery that RNA is not only a carrier of genetic information or a structural scaffold in ribonucleoprotein particles but can also act as a catalyst in many different cellular processes, greatly stimulated research on the structure, processing and function of RNA. The lecture will cover the following topics: chemistry and structure of RNA; major classes of cellular RNAs (mRNAs, tRNAs, rRNAs, snRNAs, and the newly discovered small regulatory ~20-nt RNAs); chemistry and structure of RNA; pre-mRNA processing with emphasis on splicing and polyadenylation; biogenesis of tRNA and rRNA; biochemistry and function of RNA interference (RNAi) and microRNAs; RNA trafficking in the cell, RNA quality control and RNA degradation; and regulated mRNA translation during development. Also covered are RNA-protein interactions and major classes of ribonucleoprotein particles and the evolution of RNAs.
Weblink Graduate Teaching Program


Language of instruction English
Use of digital media Online, optional


Interval weekly
Date 23.09.2021 – 23.12.2021
Time Thursday, 10.00-12.00 Friedrich Miescher Institut (FMI), Seminarraum

Seminarraum 5.30

No dates available. Please contact the lecturer.

Modules Cycle G: Molecular Biology (Master's Studies: Molecular Biology)
Doctorate Biochemistry: Recommendations (PhD subject Biochemistry)
Doctorate Biophysics: Recommendations (PhD subject Biophysics)
Doctorate Cell Biology: Recommendations (PhD subject Cell Biology)
Doctorate Computational Biology: Recommendations (PhD subject Computational Biology)
Doctorate Genetics: Recommendations (PhD subject Genetics)
Doctorate Microbiology: Recommendations (PhD subject Microbiology)
Doctorate Molecular Biology: Recommendations (PhD subject Molecular Biology)
Doctorate Neurobiology: Recommendations (PhD subject Neurobiology)
Doctorate Pharmacology: Recommendations (PhD subject Pharmacology)
Doctorate Structural Biology: Recommendations (PhD subject Structural Biology)
Module Specialisation: Molecular Biology (Master's Studies: Nanosciences)
Assessment format continuous assessment
Assessment registration/deregistration Reg./dereg.: course registr./cancel registr. via MOnA
Repeat examination no repeat examination
Scale Pass / Fail
Repeated registration as often as necessary
Responsible faculty Faculty of Science,
Offered by Departement Biozentrum