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| Semester | fall semester 2021 |
| Course frequency | Every 2nd fall sem. |
| Lecturers |
Marc Bühler (marc.buehler@unibas.ch, Assessor)
Helge Grosshans (helge.grosshans@unibas.ch) |
| Content | The discovery that RNA is not only a carrier of genetic information or a structural scaffold in ribonucleoprotein particles but can also act as a catalyst in many different cellular processes, greatly stimulated research on the structure, processing and function of RNA. The lecture will cover the following topics: chemistry and structure of RNA; major classes of cellular RNAs (mRNAs, tRNAs, rRNAs, snRNAs, and the newly discovered small regulatory ~20-nt RNAs); chemistry and structure of RNA; pre-mRNA processing with emphasis on splicing and polyadenylation; biogenesis of tRNA and rRNA; biochemistry and function of RNA interference (RNAi) and microRNAs; RNA trafficking in the cell, RNA quality control and RNA degradation; and regulated mRNA translation during development. Also covered are RNA-protein interactions and major classes of ribonucleoprotein particles and the evolution of RNAs. |
| Weblink | Graduate Teaching Program |
| Language of instruction | English |
| Use of digital media | Online, optional |
| Interval | weekly |
| Date | 23.09.2021 – 23.12.2021 |
| Time |
Thursday, 10.00-12.00 Friedrich Miescher Institut (FMI), Seminarraum Seminarraum 5.30 |
No dates available. Please contact the lecturer.
| Modules |
Cycle G: Molecular Biology (Master's Studies: Molecular Biology) Doctorate Biochemistry: Recommendations (PhD subject Biochemistry) Doctorate Biophysics: Recommendations (PhD subject Biophysics) Doctorate Cell Biology: Recommendations (PhD subject Cell Biology) Doctorate Computational Biology: Recommendations (PhD subject Computational Biology) Doctorate Genetics: Recommendations (PhD subject Genetics) Doctorate Microbiology: Recommendations (PhD subject Microbiology) Doctorate Molecular Biology: Recommendations (PhD subject Molecular Biology) Doctorate Neurobiology: Recommendations (PhD subject Neurobiology) Doctorate Pharmacology: Recommendations (PhD subject Pharmacology) Doctorate Structural Biology: Recommendations (PhD subject Structural Biology) Module Specialisation: Molecular Biology (Master's Studies: Nanosciences) |
| Assessment format | continuous assessment |
| Assessment registration/deregistration | Reg./dereg.: course registr./cancel registr. via MOnA |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Biozentrum |