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| Semester | fall semester 2021 |
| Course frequency | Irregular |
| Lecturers | Peter Maienfisch (peter.maienfisch@unibas.ch, Assessor) |
| Content | An introduction to modern life science research and development is provided, with emphasis on the discovery and optimization of bioactive compounds. The field of crop protection is discussed in detail and cross-references are made to the pharmaceutical industry and drug discovery The following topics will be covered: The life science markets with a focus on modern agribusiness - markets, benefits and challenges Current trends in life science research Case studies on the discovery and optimization of bioactive compounds Design of bioactive compounds – bioisosterism, scaffold hopping, privileged structures Product safety assessment and registration with examples from agrochemicals Modern formulation technology Patent protection This course includes a half day visit of the Syngenta Research Campus in Stein including a tour through the biological testing and chemistry facilities followed by a round table discussion with leading scientists (depend on the Covid-19 situation). |
| Learning objectives | Basic knowledge of life science R&D and of the fundamental design principles in crop protection research and medicinal chemistry. Awareness of current research approaches, trends, and highlights. |
| Bibliography | Recent Highlights in the Discovery and Optimization of Crop Protection Products, Elsevier Book, 2021 Modern Crop Protection Compounds, Volumes 1-3, Third Edition, WILEY-VCH Book, 2019 The Influence of Bioisosteres in Drug Design, 2015, N. A. Meanwell |
| Course application | Register on MOnA. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Wednesday | 16.15-19.00 | Chemie, Organische, Kleiner Hörsaal OC |
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module: Mixed Topics (Master's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment details | The students are required to perform a semester study on a hot topic in crop protection research. Depending on the number of participants the semester study is either an individual or a group work. A short written report as well as a short presentation at the end of the semester is expected. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |