| Semester | fall semester 2023 |
| Course frequency | Every 2nd fall sem. |
| Lecturers |
Michael N. Hall (m.hall@unibas.ch, Assessor)
Alexander Schmidt (alex.schmidt@unibas.ch) Nicolas Thomä (nicolas.thoma@unibas.ch) |
| Content | This course will describe the components of the translational apparatus and their putative roles in each of the three steps of protein synthesis: initiation, elongation, and termination. The first part of the course will draw information from the current literature to cover specific cases of translational control. The translational control section will cover a wide spectrum of topics including frame shifting, attenuation, phosphorylation, and transformation. The second part of the course will emphasize the role of translational control in the regulation of cell growth, with particular emphasis on the TOR signaling network. Once synthesized, proteins often require posttranslational modifications either to achieve their full biological activity or to regulate their activity. In these lectures we will discuss the various forms of posttranslational modifications of proteins and the consequences of these modifications for protein function. The lectures will give an up-to-date overview of protein splicing, poly-protein processing, different forms of modifications of amino acids, protein folding and protein transport phenomena requiring proteolysis. |
| Weblink | Graduate Teaching Program |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|
No dates available. Please contact the lecturer.
| Modules |
Cycle G: Gene Expression and Epigenetics (Master's Studies: Molecular Biology) Doctorate Biochemistry: Recommendations (PhD subject: Biochemistry) Doctorate Biophysics: Recommendations (PhD subject: Biophysics) Doctorate Cell Biology: Recommendations (PhD subject: Cell Biology) Doctorate Computational Biology: Recommendations (PhD subject: Computational Biology) Doctorate Genetics: Recommendations (PhD subject: Genetics) Doctorate Microbiology: Recommendations (PhD subject: Microbiology) Doctorate Molecular Biology: Recommendations (PhD subject: Molecular Biology) Doctorate Neurobiology: Recommendations (PhD subject: Neurobiology) Doctorate Pharmacology: Recommendations (PhD subject: Pharmacology) Doctorate Structural Biology: Recommendations (PhD subject: Structural Biology) Module Specialisation: Molecular Biology (Master's Studies: Nanosciences) |
| Assessment format | continuous assessment |
| Assessment details | Detailed information on ADAM workspace. https://adam.unibas.ch/login.php. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | Pass / Fail |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Biozentrum |