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43058-01 - Lecture: Total synthesis of natural products (3 CP)
| Semester | fall semester 2024 |
| Course frequency | Irregular |
| Lecturers |
Olivier Baudoin (olivier.baudoin@unibas.ch, Assessor)
Christof Sparr (christof.sparr@unibas.ch) |
| Content | Main concepts of multi-step synthesis and retrosynthetic analysis Synthesis of acyclic systems Synthesis of cyclic and polycyclic systems Many examples and applications |
| Learning objectives | Understand retrosynthetic analysis of complex molecules Construct key bonds and structural motifs using classical reactions and reaction sequences Control chemoselectivity and stereoselectivity issues |
| Bibliography | Classics in total synthesis, K. C. Nicolaou, E. J. Sorensen, Wiley VCH, 1996 Classics in total synthesis II, K. C. Nicolaou, S. A. Snyder, Wiley VCH, 2003 Classics in total synthesis III, K. C. Nicolaou, J. S. Chen, Wiley VCH, 2011 Organic Synthesis workbook II, C. Bittner et al., Wiley VCH, 2001 Organic Synthesis workbook III, T. Kinzel et al., Wiley VCH, 2007 Strategic applications of named reactions in organic synthesis, L. Kürti, B. Czakó, Elsevier, 2005 |
| Comments | Please download course material and print before first lecture. Lectures start at 9:00 and end up at 11:30 including a 15 min break. 19.09-14.11: O. Baudoin 21.11-19.12: C. Sparr |
| Admission requirements | Strong background in synthetic chemistry (OC0-IV or equivalent). |
| Course application | Register on services.unibas.ch |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Thursday | 09.00-11.45 | Chemie, Physikalische, Kleiner Hörsaal PC 4.04 |
Dates
| Modules |
Doctorate Chemistry: Recommendations (PhD subject: Chemistry) Module Specialisation: Chemistry (Master's Studies: Nanosciences) Module: Organic Chemistry (Master's Studies: Chemistry) |
| Assessment format | continuous assessment |
| Assessment details | Oral examination (presentation/questions) in January. |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Chemie |