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44812-01 - Lecture: Mechanisms of Toxicity (1 CP)
| Semester | fall semester 2024 |
| Course frequency | Every fall sem. |
| Lecturers |
Christian Appenzeller-Herzog (christian.appenzeller@unibas.ch)
Jamal Bouitbir (jamal.bouitbir@unibas.ch, Assessor) Alex Odermatt (alex.odermatt@unibas.ch) |
| Content | The following mechanisms will be discussed: general principles of interaction with cells and proteins, repair mechanisms, mitochondrial respiratory chain, uncoupling, mitochondrial DNA, mitochondrial fatty acid oxidation. ER stress response, redox reactions, lysosomes, phospholipidosis, cytokines, inflammasome, apoptosis, necrosis, nuclear receptors, and ion homeostasis. |
| Learning objectives | At the end of this series of lectures, students should understand the general principles of toxicological mechanisms and should understand how toxicants can damage cellular organelles and cells. |
| Bibliography | Klaassen CD, Casarett and Doull's Essentials of Toxicology. McGraw-Hill. Newest edition. Klaassen CD. Casarett and Doull's Toxicology, the basic Science of Poisons. McGraw-Hill. Newest edition. |
| Comments | Film and sound recordings during the course are strictly forbidden (recorders may be confiscated). |
| Weblink | Department of Pharmaceutical Sciences |
| Admission requirements | Completed Bachelor degree. |
| Language of instruction | English |
| Use of digital media | No specific media used |
| Interval | Weekday | Time | Room |
|---|---|---|---|
| wöchentlich | Tuesday | 13.15-15.00 | Pharmazentrum, Hörsaal 2 |
Dates
| Date | Time | Room |
|---|---|---|
| Tuesday 17.09.2024 | 13.15-15.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 24.09.2024 | 13.15-15.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 01.10.2024 | 13.15-15.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 08.10.2024 | 13.15-15.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 15.10.2024 | 13.15-15.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 22.10.2024 | 13.15-15.00 | Pharmazentrum, Hörsaal 2 |
| Tuesday 29.10.2024 | 14.00-15.00 | Biozentrum, Hörsaal U1.101 |
| Modules |
Electives Master Science in Pharmacy: Recommendations (Master's Studies: Science in Pharmacy) Module: Translating Pharmacology and Drug Safety to Humans (Master's Studies: Drug Sciences) |
| Assessment format | continuous assessment |
| Assessment details | Refer to this link:https://pharma.unibas.ch/en/education/assessments-and-credit-points/continuous-assessments/ |
| Assessment registration/deregistration | Reg.: course registration, dereg: cancel course registration |
| Repeat examination | no repeat examination |
| Scale | 1-6 0,5 |
| Repeated registration | as often as necessary |
| Responsible faculty | Faculty of Science, studiendekanat-philnat@unibas.ch |
| Offered by | Departement Pharmazeutische Wissenschaften |